CLINICAL TRIALS PROFILE FOR BEVACIZUMAB
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Biosimilar Clinical Trials for bevacizumab
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Laboratorio Elea Phoenix S.A. | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Laboratorio Elea S.A.C.I.F. y A. | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Libbs Farmacêutica LTDA | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | mAbxience S.A | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02450981 ↗ | Evaluation the Pharmacokinetics, Safety, Tolerability of BCD-021 in Patients With Neovascular Age-related Macular Degeneration | Withdrawn | Biocad | Phase 1 | 1969-12-31 | This clinical study is a phase 1 study which carried out to to evaluate the safety, pharmacokinetics and tolerability of multiple intravitreal injections of BCD-021(bevacizumab biosimilar candidate manufactured by CJSC BIOCAD, Russia) when used in patients with neovascular wet age-related macular degeneration. |
NCT02754882 ↗ | A Study Comparing SB8 and Avastin® in Patients With Advanced Non-squamous Non-small Cell Lung Cancer | Completed | Samsung Bioepis Co., Ltd. | Phase 3 | 2016-07-05 | This study is designed to establish biosimilarity of SB8, a proposed biosimilar product of bevacizumab, to EU-sourced bevacizumab, in patients with metastatic or recurrent non-squamous non-small cell lung cancer (NSCLC). |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
All Clinical Trials for bevacizumab
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00006786 ↗ | Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer | Completed | National Cancer Institute (NCI) | Phase 2 | 2000-11-01 | RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer. |
NCT00006786 ↗ | Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer | Completed | Eastern Cooperative Oncology Group | Phase 2 | 2000-11-01 | RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | National Cancer Institute (NCI) | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | University of Maryland Greenebaum Cancer Center | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | University of Maryland | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | University of Maryland, Baltimore | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for bevacizumab
Condition Name
Clinical Trial Locations for bevacizumab
Trials by Country
Clinical Trial Progress for bevacizumab
Clinical Trial Phase
Clinical Trial Sponsors for bevacizumab
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