National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Phase 4
1969-12-31
This project will provide relevant clinical information for primary care practitioners
treating alcohol withdrawal syndrome in outpatient settings. This double-blind, placebo-
controlled clinical trial will compare the effectiveness of lorazepam (Ativan) and
carbamazepine (Tegretol) in alcoholics who meet the criteria for a diagnosis of uncomplicated
alcohol withdrawal syndrome. Participants are randomized to five days of treatment with a
1-week posttreatment followup.
Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma
Completed
National Cancer Institute (NCI)
Phase 1
2000-08-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of irinotecan plus temozolomide in treating
patients who have recurrent primary malignant glioma.
Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma
Completed
Duke University
Phase 1
2000-08-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of irinotecan plus temozolomide in treating
patients who have recurrent primary malignant glioma.
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