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Last Updated: April 30, 2024

Details for Patent: 10,519,146


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Which drugs does patent 10,519,146 protect, and when does it expire?

Patent 10,519,146 protects LUMAKRAS and is included in one NDA.

This patent has sixty-one patent family members in thirty-five countries.

Summary for Patent: 10,519,146
Title:KRAS G12C inhibitors and methods of using the same
Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
Inventor(s): Lanman; Brian Alan (Thousand Oaks, CA), Chen; Jian (Thousand Oaks, CA), Reed; Anthony B. (Thousand Oaks, CA), Cee; Victor J. (Thousand Oaks, CA), Liu; Longbin (Thousand Oaks, CA), Kopecky; David John (Thousand Oaks, CA), Lopez; Patricia (Thousand Oaks, CA), Wurz; Ryan Paul (Thousand Oaks, CA), Nguyen; Thomas T. (Thousand Oaks, CA), Booker; Shon (Thousand Oaks, CA), Nishimura; Nobuko (Thousand Oaks, CA), Shin; Youngsook (Thousand Oaks, CA), Tamayo; Nuria A. (Thousand Oaks, CA), Allen; John Gordon (Thousand Oaks, CA), Allen; Jennifer Rebecca (Thousand Oaks, CA)
Assignee: Amgen Inc. (Thousand Oaks, CA)
Application Number:15/984,855
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound;

Drugs Protected by US Patent 10,519,146

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Amgen Inc LUMAKRAS sotorasib TABLET;ORAL 214665-001 May 28, 2021 RX Yes No ⤷  Try a Trial ⤷  Try a Trial Y Y ⤷  Try a Trial
Amgen Inc LUMAKRAS sotorasib TABLET;ORAL 214665-002 Jan 20, 2023 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial Y Y ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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