Details for Patent: 6,569,883
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| Title: | Medicaments |
| Abstract: | The invention relates to the use of compounds of the general formula (I) ##STR1## wherein R.sup.1 represents a hydrogen atom or a C.sub.1-10 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkyl-(C.sub.1-4)alkyl, C.sub.3-6 alkenyl, C.sub.3-10 alkynyl, phenyl or phenyl-C.sub.1-3 alkyl group; and one of the groups represented by R.sup.2, R.sup.3 and R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-6 alkenyl or phenyl-C.sub.1-3 alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkyl group; and physiologically acceptable salts and solvates thereof, for the relief of nausea and vomiting and/or the promotion of gastric emptying and for the manufacture of a medicament for this purpose. |
| Inventor(s): | Tyers; Michael Brian (Welwyn, GB), Coates; Ian Harold (Hertford, GB), Humber; David Cedric (London, GB), Ewan; George Blanch (Gerrards Cross, GB), Bell; James Angus (Royston, GB) |
| Assignee: | Glaxo Group Limited (Greenford, GB) |
| Filing Date: | May 05, 1999 |
| Application Number: | 09/305,194 |
| Claims: | 1. A pharmaceutical composition comprising an effective amount of R-1,2,3,9-tetrahydro-3-[(2-methyl-1H-imidazol-1-yl)methyl]-9-methyl-4H-car bazol-4-one hydrochloride dihydrate adapted for rectal administration. |
