Details for Patent: 5,142,051
✉ Email this page to a colleague
Summary for Patent: 5,142,051
| Title: | N-phosphonylmethoxyalkyl derivatives of pyrimidine and purine bases and a therapeutical composition therefrom with antiviral activity |
| Abstract: | This invention relates to new nucleotide analogues and solves the technical problem of their use as biologically active compounds. The subject of this invention are N-(2-phosphonylmethoxyethyl) and N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of pyrimidine and purine bases, easily accessible from heterocyclic bases andd their N-(2-hydroxyethyl) or N-(2,3-dihydroxypropyl) derivatives. Some of the compounds, according to this invention, exhibit a marked antiviral activity or can be converted into such active compounds by chemical transformations. |
| Inventor(s): | Holy; Antonin (Horni Pocernice, CS), Rosenberg; Ivan (Praha, CS), De Clercq; Erik D. A. (Leuven, BE) |
| Assignee: | Ceskoslovenska Akademie Ved (Praha, CS) Rega Institut (Leuven, BE) |
| Application Number: | 07/074,900 |
|
Patent Claim Types: see list of patent claims | Compound; |
Drugs Protected by US Patent 5,142,051
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,142,051
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Czechoslovakia | 5469-86 | Jul 18, 1986 |
International Family Members for US Patent 5,142,051
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Austria | 57932 | ⤷ Try a Trial | |||
| Australia | 600002 | ⤷ Try a Trial | |||
| Australia | 7575987 | ⤷ Try a Trial | |||
| Canada | 1340856 | ⤷ Try a Trial | |||
| Czechoslovakia | 264222 | ⤷ Try a Trial | |||
| Czechoslovakia | 8605469 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
