Details for Patent: 5,420,319
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Summary for Patent: 5,420,319
Title: | Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same |
Abstract: | Disclosed is cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and no toxicity and exhibiting anticancer performance, as shown in the below Formula. Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex of the invention possesses high optical purity or 99.94% or more e.e. and a melting point of 198.3.degree. to 199.7.degree. C. The complex is synthesized employing as starting material trans-1-1,2-cyclohexamediamine or a derivative of the trans-1-1,2-cyclohexanediamine optically resoluted by means of a high performance liquid chromatography. ##STR1## |
Inventor(s): | Okamoto; Koji (Kanagawa, JP), Nakanishi; Chihiro (Kanagawa, JP), Taniuchi; Junichi (Kanagawa, JP), Ohnishi; Junji (Kanagawa, JP), Komoda; Yasunobu (Kanagawa, JP) |
Assignee: | Tanaka Kikinzoku Kogyo K.K. (JP) |
Application Number: | 08/117,892 |
Patent Claim Types: see list of patent claims | Compound; Process; |
Drugs Protected by US Patent 5,420,319
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,420,319
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Japan | 5-142824 | May 21, 1993 |
International Family Members for US Patent 5,420,319
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Germany | 69331048 | ⤷ Try a Trial | |||
European Patent Office | 0625523 | ⤷ Try a Trial | |||
Spain | 2167328 | ⤷ Try a Trial | |||
Japan | 3025602 | ⤷ Try a Trial | |||
Japan | H06329692 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |