Details for Patent: 6,500,454
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Summary for Patent: 6,500,454
Title: | Timed, sustained release systems for propranolol |
Abstract: | A unit dosage form, such as a capsule or the like for delivering drugs into the body in a circadian release fashion, is comprising of one or more populations of propranolol-containing particles (beads, pellets, granules, etc.). Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release cardiovascular drug delivery system is designed to provide a plasma concentration--time profile, which varies according to physiological need during the day, i.e., mimicking the circadian rhythm and severity/manifestation of a cardiovascular disease, predicted based on pharmaco-kinetic and pharmaco-dynamic considerations and in vitro/in vivo correlations. |
Inventor(s): | Percel; Phillip J. (Troy, OH), Vishnupad; Krishna S. (Dayton, OH), Venkatesh; Gopi M. (Dayton, OH) |
Assignee: | Eurand Pharmaceuticals Ltd. (IE) |
Application Number: | 09/971,167 |
Patent Claim Types: see list of patent claims | Formulation; Compound; Dosage form; Device; Composition; Use; Delivery; |
Drugs Protected by US Patent 6,500,454
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 6,500,454
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 442134 | ⤷ Try a Trial | |||
Australia | 2002330211 | ⤷ Try a Trial | |||
Canada | 2462637 | ⤷ Try a Trial | |||
Germany | 60233668 | ⤷ Try a Trial | |||
European Patent Office | 1432411 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |