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|Title:||Crystalline form of indole derivative and pharmaceutical method thereof|
|Abstract:||A physical form of N-[4-[5 -(cyclopentyloxycarbonyl)amino-1-methyl-indol-3-ylmethyl]-3-methoxybenzoyl ]-2-methylbenzenesulphonamide substantially free of other physical forms, which form is crystalline, has an X-ray powder diffraction pattern with specific peaks occuring at 2.theta.=8.1, 13.7, 16.4, 20.5 and 23.7.degree. and an infra-red spectrum (0.5% in KBr) having sharp peaks at 3370, 1670, 1525, 1490, 1280, 890, 870 and 550 cm.sup.-1, a process for its preparation and pharmaceutical compositions containing it. Also disclosed is a flowable preparation of the physical form which is in the form of soft pellets, and a process for obtaining this preparation.|
|Inventor(s):||Edwards; Martin P. (Bollington, GB2), Sherwood; John D. (Congleton, GB2)|
|Assignee:||Imperial Chemical Industries plc (London, GB2)|
Patent Claim Types:|
see list of patent claims
|Compound; Composition; Delivery; Use;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|United Kingdom||9027018||Dec 12, 1990|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Hong Kong||81497||Jun 27, 1997|
|European Patent Office||0490649||Jun 17, 1992|
|United Kingdom||2250743||Jun 17, 1992|
|This preview shows a limited data set|
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