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Details for Patent: 5,294,636

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Summary for Patent: 5,294,636

Title: Crystalline form of indole derivative and pharmaceutical method thereof
Abstract:A physical form of N-[4-[5 -(cyclopentyloxycarbonyl)amino-1-methyl-indol-3-ylmethyl]-3-methoxybenzoyl ]-2-methylbenzenesulphonamide substantially free of other physical forms, which form is crystalline, has an X-ray powder diffraction pattern with specific peaks occuring at 2.theta.=8.1, 13.7, 16.4, 20.5 and 23.7.degree. and an infra-red spectrum (0.5% in KBr) having sharp peaks at 3370, 1670, 1525, 1490, 1280, 890, 870 and 550 cm.sup.-1, a process for its preparation and pharmaceutical compositions containing it. Also disclosed is a flowable preparation of the physical form which is in the form of soft pellets, and a process for obtaining this preparation.
Inventor(s): Edwards; Martin P. (Bollington, GB2), Sherwood; John D. (Congleton, GB2)
Assignee: Imperial Chemical Industries plc (London, GB2)
Application Number:07/805,426
Patent Claim Types:
see list of patent claims
Compound; Composition; Delivery; Use;
Patent PDF download available with subscription

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Patented / Exclusive Use
Astrazeneca
ACCOLATE
zafirlukast
Tablet; Oral020547-001SEP 26, 1996RXYes5,294,636<disabled>
Astrazeneca
ACCOLATE
zafirlukast
Tablet; Oral020547-003SEP 17, 1999RXNo5,294,636<disabled>
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Foreign Priority and PCT Information for Patent: 5,294,636

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9027018Dec 12, 1990

International Patent Family for Patent: 5,294,636

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Slovakia279018May 06, 1998
Greece3021605Feb 28, 1997
Hungary211125Oct 30, 1995
Denmark0490649Apr 21, 1997
Canada2056067Jun 13, 1992
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Copyright 2002-2015 thinkBiotech LLC
ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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