Claims for Patent: 5,385,839

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Summary for Patent: 5,385,839

Title:	Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter regulatory DNA sequence
Abstract:	The cloning of a eucaryotic promoter-regulatory region that functions preferentially in human cells is disclosed. The invention is exemplified by the cloning of a section of the human cytomegalovirus genome comprising a DNA sequence with regulatory and promoter signals and an initiation site for RNA synthesis. The fragment, termed the human cytomegalovirus (HCMV) promoter-regulatory sequence, was obtained from purified HCMV DNA.
Inventor(s):	Stinski; Mark F. (Iowa City, IA)
Assignee:	University of Iowa Research Foundation (Iowa City, IA)
Application Number:	07/900,056
Patent Claims:	1. A transfer vector comprising the immediate-early promoter-regulatory region of human cytomegalovirus. 2. The transfer vector of claim 1 comprising a heterologous gene positioned downstream and operatively linked to said region. 3. A host cell transformed with the transfer vector of claim 1. 4. A host cell transformed with the transfer vector of claim 2. 5. A eucaryotic host cell transformed with a transfer vector comprising the immediate-early promoter-regulatory region of human cytomegalovirus and a heterologous gene positioned downstream and operatively linked to said region. 6. The transformed eucaryotic host cell of claim 5 wherein said host cell is a mammalian host cell. 7. A host cell engineered using recombinant DNA technology to contain the immediate-early, promoter-regulatory region of human cytomegalovirus.

Details for Patent 5,385,839

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	November 23, 2004	⤷ Sign Up	2005-01-30
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,385,839

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Country	Patent Number	Estimated Expiration
United States of America	5168062	⤷ Sign Up
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