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Last Updated: December 15, 2024

Patent: 9,181,337


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Summary for Patent: 9,181,337
Scope and claims summary:
Title:Modulated lysine variant species compositions and methods for producing and using the same
Abstract: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided.
Inventor(s): Subramanian; Kartik (Northborough, MA), Perez Thiele; Mayda (Vega Alta, PR), Zeng; Xiaobei (Carolina, PR), Wong; Chee Furng (Singapore, SG), Kaymakcalan; Zehra (Westborough, MA), Jing; Ying (Wellesley, MA), Chumsae; Christopher (North Andover, MA)
Assignee: AbbVie, Inc. (North Chicago, IL)
Application Number:14/077,988
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 9,181,337
Patent Claims:see list of patent claims

Details for Patent 9,181,337

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 December 31, 2002 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 February 21, 2008 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 April 24, 2013 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 September 23, 2014 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 November 23, 2015 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 March 09, 2016 9,181,337 2033-10-18
Abbvie Inc. HUMIRA adalimumab Injection 125057 October 17, 2016 9,181,337 2033-10-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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