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Last Updated: January 6, 2025

BEXSERO Drug Profile


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Summary for Tradename: BEXSERO
High Confidence Patents:0
Applicants:1
BLAs:1
Recent Clinical Trials: See clinical trials for BEXSERO
Recent Clinical Trials for BEXSERO

Identify potential brand extensions & biosimilar entrants

SponsorPhase
University of North Carolina, Chapel HillPhase 2
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
Thomas BenfieldPhase 4

See all BEXSERO clinical trials

Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for BEXSERO Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for BEXSERO Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for BEXSERO Derived from Patent Text Search

These patents were obtained by searching patent claims

BEXSERO Market Analysis and Financial Projection

Market Dynamics and Financial Trajectory for BEXSERO

Introduction to BEXSERO

BEXSERO is a meningococcal group B vaccine developed by GSK (GlaxoSmithKline) to protect against meningococcal infections caused by serotype B. This vaccine has been a significant player in the global meningococcal vaccines market, driven by its high efficacy and widespread approval.

Market Size and Growth

The global meningococcal vaccines market, within which BEXSERO operates, has been experiencing robust growth. As of 2021, the global meningococcal vaccines market was valued at USD 2.88 billion and is projected to reach USD 5.07 billion by 2030, growing at a CAGR of 6.5% during the forecast period[1].

Segment Performance

Vaccine Type

BEXSERO falls under the conjugate vaccines segment, which is a key driver of the market. Conjugate vaccines, including BEXSERO, offer enhanced protection and improved safety profiles compared to traditional polysaccharide vaccines[3].

Brand Performance

BEXSERO is one of the leading brands in the meningococcal vaccines market. It is approved for use in over 40 countries, including New Zealand, Argentina, Chile, Australia, Israel, Uruguay, Turkey, and several European countries. The high acceptance rate of BEXSERO can be attributed to its effectiveness against meningococcal serotype B infections, which are particularly severe and sometimes life-threatening[1].

Drivers of Growth

Increasing Prevalence of Meningococcal Disease

The rising incidence of meningococcal disease globally is a significant driver for the market. Meningococcal disease can lead to severe conditions such as meningitis and septicemia, highlighting the urgent need for effective vaccination programs. This has led to increased demand for vaccines like BEXSERO[3].

Government Initiatives and Immunization Programs

Favorable government initiatives and extensive immunization programs worldwide have boosted the demand for meningococcal vaccines. These programs, especially in regions with high incidence rates like sub-Saharan Africa, have been crucial in driving the market growth[3].

Advancements in Vaccine Technology

Continual advancements in vaccine technology, including the development of new and improved vaccines, have enhanced the market. Innovations in vaccine delivery systems and the integration of meningococcal antigens into combination vaccines have also contributed to the growth[3].

Financial Performance

Sales and Revenue

BEXSERO has contributed significantly to GSK's vaccine sales. In 2023, GSK reported strong vaccine sales, with a 25% increase in vaccine revenues, partly driven by the successful uptake of vaccines like BEXSERO. The company's vaccine segment, excluding COVID-19 solutions, saw a 24% growth, reflecting the robust demand for meningococcal vaccines[2].

Regional Performance

The Asia Pacific region is expected to be one of the fastest-growing markets for meningococcal vaccines, including BEXSERO. This growth is driven by increasing awareness, government initiatives, and the rising incidence of meningococcal disease in this region[1].

Competitive Landscape

BEXSERO operates in a competitive market with other notable brands such as Menactra, Menveo, Nimenrix, and Trumenba. However, BEXSERO's approval in over 40 countries and its high efficacy rate have positioned it as a leading player in the market. Key companies in the meningococcal vaccines market include Bio-Manguinhos, Biomed Pvt. Ltd, GlaxoSmithKline plc, Merck & Co., Inc., Novartis AG, and Pfizer Inc.[1].

Challenges and Restraints

High Costs

Despite the growth drivers, the high costs involved in vaccination programs can hamper market growth. This is particularly challenging in developing countries where access to affordable vaccines is limited[4].

Regulatory and Approval Processes

The regulatory and approval processes for vaccines can be stringent and time-consuming, which may affect the market trajectory of BEXSERO and other meningococcal vaccines.

Future Outlook

R&D and Pipeline Development

GSK continues to invest heavily in R&D, with a strong pipeline of new vaccines and medicines. This includes ongoing efforts to improve existing vaccines and develop new ones, which will likely support the continued growth of BEXSERO and the broader meningococcal vaccines market[5].

Market Projections

By 2030, the global meningococcal vaccines market is expected to reach USD 5.07 billion, with BEXSERO likely to remain a significant contributor to this growth. The market is expected to continue growing driven by increasing prevalence of meningococcal disease, advancements in vaccine technology, and favorable government initiatives[1].

Key Takeaways

  • Market Growth: The global meningococcal vaccines market, including BEXSERO, is projected to grow at a CAGR of 6.5% from 2021 to 2030.
  • Segment Performance: BEXSERO is a leading brand in the conjugate vaccines segment, approved in over 40 countries.
  • Drivers: Increasing prevalence of meningococcal disease, government initiatives, and advancements in vaccine technology drive the market.
  • Financial Performance: Strong vaccine sales, including BEXSERO, have contributed to GSK's revenue growth.
  • Challenges: High costs and regulatory processes are potential restraints.

FAQs

What is the current market size of the global meningococcal vaccines market?

The global meningococcal vaccines market was valued at USD 2.88 billion in 2021[1].

Which regions are expected to grow the fastest in the meningococcal vaccines market?

The Asia Pacific region is expected to grow the fastest during the forecast period[1].

What are the key drivers of the meningococcal vaccines market?

Key drivers include the increasing prevalence of meningococcal disease, government initiatives, and advancements in vaccine technology[3].

Which companies are the key players in the meningococcal vaccines market?

Key companies include Bio-Manguinhos, Biomed Pvt. Ltd, GlaxoSmithKline plc, Merck & Co., Inc., Novartis AG, and Pfizer Inc.[1].

What are the challenges facing the meningococcal vaccines market?

High costs involved in vaccination programs and stringent regulatory processes are significant challenges[4].

Sources

  1. Spherical Insights & Consulting, "Global Meningococcal Vaccines Market Size is projected to reach USD 5.07 Billion by 2030, growing at a CAGR of 6.5%," GlobeNewswire, November 7, 2022.
  2. GSK, "Q4 2023 Announcement," GSK, January 31, 2024.
  3. Biospace, "Meningococcal Vaccines Market to Reach USD 7.2 Billion by 2032," Biospace, August 8, 2024.
  4. Coherent Market Insights, "Meningitis Vaccines Market Report, Trends, Share & Insights," Coherent Market Insights.
  5. GSK, "Q1 2024 Results Announcement," GSK, May 1, 2024.

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