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Last Updated: December 26, 2024

TYPHIM VI Drug Profile


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Summary for Tradename: TYPHIM VI
High Confidence Patents:0
Applicants:1
BLAs:1
Recent Clinical Trials: See clinical trials for TYPHIM VI
Recent Clinical Trials for TYPHIM VI

Identify potential brand extensions & biosimilar entrants

SponsorPhase
University Hospital, LinkoepingPhase 1
Karolinska InstitutetPhase 1
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1

See all TYPHIM VI clinical trials

Pharmacology for TYPHIM VI
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for TYPHIM VI Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for TYPHIM VI Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for TYPHIM VI Derived from Patent Text Search

No patents found based on company disclosures

TYPHIM VI Market Analysis and Financial Projection Experimental

Typhoid Vi Polysaccharide Vaccine Market Dynamics and Financial Trajectory

The Typhoid Vi polysaccharide vaccine market, exemplified by products like Typhim Vi, is experiencing significant growth driven by several key factors. Here’s a detailed look at the market dynamics and financial trajectory of this segment.

Market Size and Growth Rate

The global Typhoid Vi polysaccharide vaccine market has been expanding rapidly. In 2023, the market size was valued at $4.98 billion and is projected to grow to $5.84 billion in 2024, representing a compound annual growth rate (CAGR) of 17.3%[1][3][5].

Forecasted Growth

Looking ahead, the market is expected to continue its robust growth, reaching $11.28 billion by 2028 at a CAGR of 17.9%. By 2030, the market is projected to reach $13.28 billion, growing at a CAGR of 18.9% during the forecast period 2024-2030[1][3][5].

Drivers of the Market

Several factors are driving the growth of the Typhoid Vi polysaccharide vaccine market:

Disease Prevalence

The prevalence of typhoid fever, particularly in regions with poor sanitation and hygiene, is a significant driver. Typhoid remains a major public health concern in many developing countries[1][3][5].

Global Health Initiatives

Global health initiatives and expanded immunization programs are crucial in increasing the demand for these vaccines. Organizations like the World Health Organization (WHO) and UNICEF play a vital role in promoting vaccination campaigns[1][3][4].

Traveler Vaccination

Increased travel to endemic areas has led to a higher demand for typhoid vaccines among travelers, contributing to market growth[1][3].

Government Immunization Efforts

Government-led immunization campaigns and public health policies are instrumental in driving the market forward. These efforts often include routine immunization activities and catch-up campaigns[1][3][4].

Vaccine Efficacy and Safety

The efficacy and safety of Typhoid Vi polysaccharide vaccines are well-documented, which enhances their adoption and use[1][3].

Healthcare Expenditure

Growing healthcare expenditure is another pivotal factor. In the United States, for example, healthcare expenditure is projected to reach nearly $6.0 trillion by 2027, with an average annual growth rate of 5.5% from 2018. This increased spending supports the development and distribution of more typhoid vaccines[1][3].

Market Segmentation

The market is segmented by type, route of administration, and application:

By Type

The market is segmented into vaccines for children and adults. The introduction of typhoid conjugate vaccines suitable for children from six months up to 45 years of age has expanded the market[4].

By Route of Administration

Vaccines are administered either orally or parenterally. Parenteral administration is more common for Typhoid Vi polysaccharide vaccines[1][3].

By Application

The vaccines are used in various settings, including travel medicine, public health programs, and private healthcare services[1][3].

Regional Market Dynamics

Asia-Pacific

The Asia-Pacific region is expected to see significant growth due to the high prevalence of typhoid, development of healthcare infrastructure, and rising government initiatives for immunization programs[4].

Western Europe and UK

In Western Europe and the UK, the market is driven by government initiatives, public health awareness, and the expansion of immunization programs[1][3].

Key Trends

Several trends are shaping the future of the Typhoid Vi polysaccharide vaccine market:

R&D Investments

Increased investments in research and development are leading to the development of more effective and safer vaccines[1][3].

Regulatory Support

Strengthened regulatory backing is facilitating the approval and distribution of new vaccines[1][3].

Epidemiological Studies

Enhanced epidemiological studies are helping in better understanding the disease and in targeting vaccination efforts more effectively[1][3].

Public Health Awareness

Heightened public awareness about public health issues is driving demand for vaccines and contributing to market growth[1][3].

Major Players

Key players in the market include:

Sanofi Pasteur SA

Known for their extensive portfolio of vaccines, Sanofi Pasteur SA is a major player in the Typhoid Vi polysaccharide vaccine market[1].

GlaxoSmithKline plc

GSK is another significant player, with a strong focus on vaccine development and distribution[1].

Merck & Co. Inc.

Merck & Co. Inc. is also a key player, investing heavily in R&D and expanding its vaccine offerings[1].

Pfizer Inc.

Pfizer Inc. is another major pharmaceutical company involved in the development and marketing of typhoid vaccines[1].

Johnson & Johnson Private Limited

Johnson & Johnson Private Limited is also a significant player, with a diverse range of healthcare products, including vaccines[1].

Cost-Effectiveness

Studies have shown that typhoid conjugate vaccines are highly cost-effective, especially in settings with high incidence rates. For instance, these vaccines are cost-effective when administered through routine immunization activities in settings with an annual incidence of more than 50 cases per 100,000 people[2].

"Vi conjugate typhoid vaccines were highly cost-effective when administered by routine immunization activities through the EPI in settings with an annual incidence of >50 cases/100000 (95% uncertainty interval, 40–75 cases)" - NCBI[2].

Key Takeaways

  • The Typhoid Vi polysaccharide vaccine market is growing rapidly, driven by disease prevalence, global health initiatives, and government immunization efforts.
  • The market is expected to reach $11.28 billion by 2028 and $13.28 billion by 2030.
  • Growing healthcare expenditure and increased investments in R&D are key drivers.
  • The market is segmented by type, route of administration, and application.
  • Major players include Sanofi Pasteur SA, GlaxoSmithKline plc, Merck & Co. Inc., Pfizer Inc., and Johnson & Johnson Private Limited.

FAQs

What is the current market size of the Typhoid Vi polysaccharide vaccine market?

The current market size of the Typhoid Vi polysaccharide vaccine market was valued at $4.98 billion in 2023[1][3][5].

What is the projected growth rate of the Typhoid Vi polysaccharide vaccine market?

The market is projected to grow at a CAGR of 17.9% from 2023 to 2028 and 18.9% from 2024 to 2030[1][3][5].

What are the main drivers of the Typhoid Vi polysaccharide vaccine market?

The main drivers include disease prevalence, global health initiatives, traveler vaccination, government immunization efforts, vaccine efficacy and safety, and growing healthcare expenditure[1][3][5].

Which regions are expected to see significant growth in the Typhoid Vi polysaccharide vaccine market?

The Asia-Pacific region, Western Europe, and the UK are expected to see significant growth due to various factors including disease prevalence and government initiatives[1][3][4].

Who are the major players in the Typhoid Vi polysaccharide vaccine market?

Major players include Sanofi Pasteur SA, GlaxoSmithKline plc, Merck & Co. Inc., Pfizer Inc., and Johnson & Johnson Private Limited[1].

How cost-effective are typhoid conjugate vaccines?

Typhoid conjugate vaccines are highly cost-effective in settings with high incidence rates, particularly when administered through routine immunization activities[2].

Sources

  1. The Business Research Company: Typhoid Vi Polysaccharide Vaccine Global Market Report 2024
  2. NCBI: Comparison of Strategies and Incidence Thresholds for Vi Conjugate Typhoid Vaccines
  3. Research and Markets: Typhoid Vi Polysaccharide Vaccine Global Market Report 2024
  4. UNICEF: Typhoid Conjugate Vaccine Supply and Demand Update December 2022
  5. Verified Market Research: Typhoid Vi Polysaccharide Vaccine Market Size & Forecast

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