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Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR LUMIFY


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All Clinical Trials for LUMIFY

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03782701 ↗ The Effect of Lumify™ Eyedrops on Eyelid Position Completed University of Miami Phase 4 2019-06-18 The purpose of the research is to see if Lumify™ has an effect on eyelid position.
NCT03782701 ↗ The Effect of Lumify™ Eyedrops on Eyelid Position Completed Wendy Lee Phase 4 2019-06-18 The purpose of the research is to see if Lumify™ has an effect on eyelid position.
NCT04007276 ↗ The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients Not yet recruiting Tulane University Phase 4 2025-11-10 Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects. Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) is an FDA-approved medication for alleviating eye redness, a common side effect of glaucoma medications. The purpose of this study is to evaluate the effect of Lumify™ on eye redness, intraocular pressure, and eyelid position in patients with glaucoma who are already using the Brimonidine 0.1%, 0.15% or 0.2% eye drops.
NCT04024891 ↗ Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis Completed Ocuphire Pharma, Inc. Phase 2 2019-08-13 The objectives of this study are: - To evaluate the efficacy of Nyxol (phentolamine mesylate ophthalmic solution 1%) to expedite the reversal of pharmacologic mydriasis - To evaluate the safety of Nyxol - To evaluate the effect of Lumify® to suppress conjunctival hyperemia (redness) potentially associated with administration of Nyxol
NCT04683159 ↗ Brimonidine Tartrate for Pterygium Surgery Not yet recruiting Uptown Eye Specialists N/A 2021-02-01 Pterygium excision and conjunctival autograft surgery is commonly done to treat pterygiums. Excessive bleeding during the procedure creates a challenging operating field, prolongs surgery time, and prolongs healing. Brimonidine tartrate has a vasoconstrictive effect, which helps to reduce the amount of blood flow and hyperemia to the eye. Preoperative use of brimonidine has been shown to decrease subconjunctival hemorrhage during procedures such as cataract surgery, laser assisted in situ keratomileusis, strabismus surgery, and intravitreal injections. The focus of this study is to assess the effect of preoperative application of brimonidine tartrate 0.15% (Alphagan) and 0.025% (Lumify) on reducing hemorrhage during pterygium excision and conjunctival autograft surgery.
NCT05360784 ↗ A Multi-Center, Double-Masked, Randomized, Active-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% Preservative-Free Formulation With Lumify® 0.025% in Adult Subjects With Ocular Not yet recruiting Bausch & Lomb Incorporated Phase 3 2022-05-01 This is a multi-center, double-masked, randomized, active-controlled, parallel-group, efficacy and safety study that will enroll 386 participants at up to six clinical sites. Participants with ocular redness will be randomized to receive either brimonidine tartrate ophthalmic solution 0.025%, preservative-free formulation, or Lumify® (brimonidine tartrate ophthalmic solution 0.025%). Participants will be treated with study drug for approximately 4 weeks.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for LUMIFY

Condition Name

Condition Name for LUMIFY
Intervention Trials
Glaucoma, Open-Angle 1
Glaucoma, Primary Open Angle 1
Glaucoma; Drugs 1
Mydriasis 1
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Condition MeSH

Condition MeSH for LUMIFY
Intervention Trials
Blepharoptosis 3
Dilatation, Pathologic 1
Ectropion 1
Glaucoma, Open-Angle 1
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Clinical Trial Locations for LUMIFY

Trials by Country

Trials by Country for LUMIFY
Location Trials
United States 13
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Trials by US State

Trials by US State for LUMIFY
Location Trials
Kentucky 3
Utah 1
Tennessee 1
North Carolina 1
Massachusetts 1
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Clinical Trial Progress for LUMIFY

Clinical Trial Phase

Clinical Trial Phase for LUMIFY
Clinical Trial Phase Trials
Phase 4 3
Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for LUMIFY
Clinical Trial Phase Trials
Not yet recruiting 3
Completed 2
Recruiting 1
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Clinical Trial Sponsors for LUMIFY

Sponsor Name

Sponsor Name for LUMIFY
Sponsor Trials
Bausch & Lomb Incorporated 1
University of Louisville 1
University of Miami 1
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Sponsor Type

Sponsor Type for LUMIFY
Sponsor Trials
Other 5
Industry 2
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