CLINICAL TRIALS PROFILE FOR RECLAST
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All Clinical Trials for RECLAST
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00171964 ↗ | Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions | Completed | Novartis Pharmaceuticals | Phase 4 | 2002-05-01 | It is the aim of this multicentric clinical study to assess the efficacy and tolerability of zoledronic acid in combination with radiotherapy in patients with advanced osteolytic bone lesions in terms of the reduction of pain and analgesic consumption. |
NCT00305695 ↗ | Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries | Completed | National Cancer Institute (NCI) | Phase 2 | 2005-11-28 | This randomized phase II trial is studying zoledronate to see how well it works compared to observation in maintaining bone mineral density in patients who are undergoing surgery to remove both ovaries. Zoledronate may prevent bone loss in patients who are undergoing surgery to remove the ovaries. |
NCT00305695 ↗ | Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries | Completed | Gynecologic Oncology Group | Phase 2 | 2005-11-28 | This randomized phase II trial is studying zoledronate to see how well it works compared to observation in maintaining bone mineral density in patients who are undergoing surgery to remove both ovaries. Zoledronate may prevent bone loss in patients who are undergoing surgery to remove the ovaries. |
NCT00439647 ↗ | Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis | Completed | Novartis Pharmaceuticals | Phase 3 | 2006-12-01 | This study will investigate if the drug zoledronic acid given once yearly is safe and has beneficial effects in treating osteoporosis by reducing bone loss and fractures in men with osteoporosis. |
NCT00556374 ↗ | Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy | Active, not recruiting | Austrian Breast and Colorectal Cancer Study Group | Phase 3 | 2006-12-18 | The purpose of this study is to determine whether denosumab compared to placebo, will reduce the rate of first clinical fracture in women with non-metastatic breast cancer receiving (non-steroidal) aromatase inhibitor therapy. |
NCT00556374 ↗ | Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy | Active, not recruiting | Amgen | Phase 3 | 2006-12-18 | The purpose of this study is to determine whether denosumab compared to placebo, will reduce the rate of first clinical fracture in women with non-metastatic breast cancer receiving (non-steroidal) aromatase inhibitor therapy. |
NCT00558012 ↗ | Zoledronic Acid for Osteoporosis in the Elderly | Completed | National Institute on Aging (NIA) | N/A | 2007-12-01 | This trial will examine the safety, efficacy and feasibility of a single dose of intravenous zoledronic acid in the maintenance of skeletal integrity for frail, institutionalized women, who are most at risk for the deleterious outcomes of osteoporosis. The investigators will test the hypothesis that in institutionalized elderly women a single dose of intravenous zoledronic acid therapy will: (1) be efficacious as demonstrated by stability or improvement in bone mass measurements and reductions in bone turnover; (2) be safe and feasible; and (3) provide estimates for vertebral and nonvertebral fracture reduction in this cohort for use in planning a future study. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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