Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors
Completed
Roswell Park Cancer Institute
Phase 1
2004-08-01
RATIONALE: Drugs used in chemotherapy, such as irinotecan, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Selenium may allow higher doses of irinotecan to be given. Giving irinotecan together with
selenium may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of selenium when given
together with irinotecan in treating patients with advanced solid tumors.
Selenium Supplementation of Patients With Cirrhosis
Completed
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
N/A
1998-10-01
The purpose of this study is to determine whether patients with liver disease can improve
their nutritional selenium status by taking supplemental selenium.
Selenium Supplementation of Patients With Cirrhosis
Completed
Vanderbilt University
N/A
1998-10-01
The purpose of this study is to determine whether patients with liver disease can improve
their nutritional selenium status by taking supplemental selenium.
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