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Last Updated: December 26, 2024

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CLINICAL TRIALS PROFILE FOR TYBOST

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All Clinical Trials for TYBOST

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT02503462 ↗	Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals	Terminated	University Hospital, Basel, Switzerland	Phase 4	2015-07-01	The purpose of this study is to assess whether a boosting by cobicistat results in similar concentrations of darunavir in the brain compared to a boosting by ritonavir.
NCT02565888 ↗	A Drug-drug Interaction Study Between Daclatasvir and Atazanavir/Ritonavir or Atazanavir/Cobicistat	Completed	Radboud University	Phase 1	2015-11-01	This study aims to provide the evidence that 150mg of cobicistat will have the same effect on the pharmacokinetics of daclatasvir 30mg QD as 100mg of ritonavir, when given together with atazanavir 300mg.
NCT03858491 ↗	Pharmacokinetic Boosting of Osimertinib	Recruiting	The Netherlands Cancer Institute	Early Phase 1	2020-11-01	The main objective of this study is to evaluate if systemic exposure of osimertinib (i.e. AUC) is increased when osimertinib is co-administered with cobicistat in patients with relatively low plasma trough concentration while receiving the standard osimertinib dose.
NCT03858491 ↗	Pharmacokinetic Boosting of Osimertinib	Recruiting	ZonMw: The Netherlands Organisation for Health Research and Development	Early Phase 1	2020-11-01	The main objective of this study is to evaluate if systemic exposure of osimertinib (i.e. AUC) is increased when osimertinib is co-administered with cobicistat in patients with relatively low plasma trough concentration while receiving the standard osimertinib dose.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for TYBOST

Condition Name

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Condition Name for TYBOST
Intervention	Trials
AIDS-related Dementia Complex	1
Drug-drug Interaction	1
Healthy Participants	1
Hepatitis C	1
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Condition MeSH

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Condition MeSH for TYBOST
Intervention	Trials
Carcinoma, Non-Small-Cell Lung	2
Dementia	1
AIDS Dementia Complex	1
Malnutrition	1
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Clinical Trial Locations for TYBOST

Trials by Country

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Trials by Country for TYBOST
Location	Trials
Netherlands	3
United States	2
Switzerland	1
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Trials by US State

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Trials by US State for TYBOST
Location	Trials
Arizona	1
Florida	1
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Clinical Trial Progress for TYBOST

Clinical Trial Phase

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Clinical Trial Phase for TYBOST
Clinical Trial Phase	Trials
Phase 4	2
Phase 1	3
Early Phase 1	1
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Clinical Trial Status

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Clinical Trial Status for TYBOST
Clinical Trial Phase	Trials
Completed	2
Not yet recruiting	2
Recruiting	1
[disabled in preview]	1
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Clinical Trial Sponsors for TYBOST

Sponsor Name

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Sponsor Name for TYBOST
Sponsor	Trials
University Hospital, Basel, Switzerland	1
Radboud University	1
The Netherlands Cancer Institute	1
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for TYBOST
Sponsor	Trials
Other	6
Industry	2
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