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Last Updated: November 25, 2024

CLINICAL TRIALS PROFILE FOR BENDROFLUMETHIAZIDE


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All Clinical Trials for bendroflumethiazide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00320879 ↗ Optimal Dose of Irbesartan for Renoprotection in Type 2 Diabetic Patients With Persistent Microalbuminuria Completed Steno Diabetes Center Phase 4 2003-09-01 Aim: To evaluate the renoprotective effect as reflected by short-term changes in albuminuria of ultra high doses of irbesartan in Type 2 diabetic patients with microalbuminuria Design: A double-masked randomized cross-over trial including 60 hypertensive Type 2 diabetic patients with microalbuminuria on ongoing antihypertensive medication. At inclusion, previous antihypertensive treatment will be discontinued and replaced with bendroflumethiazide 5 mg o.d. for the entire study. Following two months wash-out (baseline), patients will be treated randomly with irbesartan 300, 600 and 900 mg o.d., each dose for two months. End-points evaluated at the end of each study period include urinary albumin excretion rate (UAE, mean of three 24-hrs collections), 24-hrs blood pressure (ABP); and GFR (51Cr-EDTA).
NCT00320879 ↗ Optimal Dose of Irbesartan for Renoprotection in Type 2 Diabetic Patients With Persistent Microalbuminuria Completed Steno Diabetes Center Copenhagen Phase 4 2003-09-01 Aim: To evaluate the renoprotective effect as reflected by short-term changes in albuminuria of ultra high doses of irbesartan in Type 2 diabetic patients with microalbuminuria Design: A double-masked randomized cross-over trial including 60 hypertensive Type 2 diabetic patients with microalbuminuria on ongoing antihypertensive medication. At inclusion, previous antihypertensive treatment will be discontinued and replaced with bendroflumethiazide 5 mg o.d. for the entire study. Following two months wash-out (baseline), patients will be treated randomly with irbesartan 300, 600 and 900 mg o.d., each dose for two months. End-points evaluated at the end of each study period include urinary albumin excretion rate (UAE, mean of three 24-hrs collections), 24-hrs blood pressure (ABP); and GFR (51Cr-EDTA).
NCT00647660 ↗ Fasting Study of Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg and Corzide® Tablets 80 mg/5 mg Completed Mylan Pharmaceuticals Phase 1 2006-07-01 The objective of this study was to investigate the bioequivalence of Mylan's nadolol/bendroflumethiazide 80 mg/5 mg tablets to King's Corzide® 80 mg/5 mg tablets following a single, oral 80 mg/5 mg (1 x 80 mg/5 mg) dose administered under fasting conditions.
NCT00648297 ↗ Fed Study of Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg and Corzide® Tablets 80 mg/5 mg Completed Mylan Pharmaceuticals Phase 1 2006-08-01 The objective of this study was to investigate the bioequivalence of Mylan's nadolol/bendroflumethiazide 80 mg/5 mg tablets to King's Corzide® 80 mg/5 mg tablets following a single, oral 80 mg/5 mg (1 x 80 mg/5 mg) dose administered under fed conditions.
NCT05753059 ↗ Mechanisms of Diuretic Resistance in Heart Failure, Aim 2 Not yet recruiting Yale University Phase 1 2023-06-01 Randomized placebo-controlled, double-blind, double-dummy, crossover design testing combinations placebo/placebo, bendroflumethiazide/placebo, amiloride/placebo, and bendroflumethiazide/amiloride added to bumetanide.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for bendroflumethiazide

Condition Name

Condition Name for bendroflumethiazide
Intervention Trials
Healthy 2
Type 2 Diabetes 1
Heart Failure 1
Microalbuminuria 1
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Condition MeSH

Condition MeSH for bendroflumethiazide
Intervention Trials
Heart Failure 1
Albuminuria 1
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Clinical Trial Locations for bendroflumethiazide

Trials by Country

Trials by Country for bendroflumethiazide
Location Trials
United States 2
Denmark 1
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Trials by US State

Trials by US State for bendroflumethiazide
Location Trials
North Dakota 2
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Clinical Trial Progress for bendroflumethiazide

Clinical Trial Phase

Clinical Trial Phase for bendroflumethiazide
Clinical Trial Phase Trials
Phase 4 1
Phase 1 3
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Clinical Trial Status

Clinical Trial Status for bendroflumethiazide
Clinical Trial Phase Trials
Completed 3
Not yet recruiting 1
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Clinical Trial Sponsors for bendroflumethiazide

Sponsor Name

Sponsor Name for bendroflumethiazide
Sponsor Trials
Mylan Pharmaceuticals 2
Steno Diabetes Center 1
Steno Diabetes Center Copenhagen 1
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Sponsor Type

Sponsor Type for bendroflumethiazide
Sponsor Trials
Other 3
Industry 2
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