CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride
Completed
Janssen Research & Development, LLC
Phase 3
2009-09-01
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of
canagliflozin (JNJ-28431754) compared with glimepiride in patients with type 2 diabetes
mellitus with inadequate control despite treatment with metformin.
The CANTATA-M (CANagliflozin Treatment and Trial Analysis - Monotherapy) Trial
Completed
Janssen Research & Development, LLC
Phase 3
2010-03-01
The purpose of this study is to evaluate the efficacy, safety, and tolerability of 2
different doses of canagliflozin administered as monotherapy compared with placebo in
patients with type 2 diabetes mellitus (T2DM) inadequately controlled with diet and exercise.
The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea)
Completed
Janssen Research & Development, LLC
Phase 3
2010-05-01
The purpose of this study is to evaluate the efficacy and safety of 2 different doses of
canagliflozin compared with placebo in patients with type 2 diabetes mellitus who are
receiving treatment with metformin and sulphonylurea and have inadequate glycemic (blood
sugar) control.
The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)
Completed
Janssen Research & Development, LLC
Phase 3
2010-05-01
The purpose of this study is to evaluate the efficacy and safety of canagliflozin compared
with sitagliptin and placebo in patients with type 2 diabetes mellitus who are receiving
treatment with metformin monotherapy (i.e., treatment with a single drug) and have inadequate
glycemic (blood sugar) control.
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