Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis
Completed
GlaxoSmithKline
N/A
2006-07-01
The aim of this study is to assess the efficacy on nasal congestion and other allergic
symptoms and the onset of action of an oral combination of cetirizine and pseudoephedrine in
comparison to the single substances under controlled pollen exposure in an Environmental
Challenge Chamber (ECC).
Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis
Completed
Fraunhofer-Institute of Toxicology and Experimental Medicine
N/A
2006-07-01
The aim of this study is to assess the efficacy on nasal congestion and other allergic
symptoms and the onset of action of an oral combination of cetirizine and pseudoephedrine in
comparison to the single substances under controlled pollen exposure in an Environmental
Challenge Chamber (ECC).
Study to Compare the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Placebo on Symptoms in Patients With Allergic Rhinitis Within/Out of Season
Completed
Fraunhofer-Institute of Toxicology and Experimental Medicine
N/A
2007-06-01
A previous study has shown very clearly that the treatment with the combination of cetirizine
and pseudoephedrine is superior to the treatment with the single agents regarding the
reduction of symptoms in patients with allergic rhinitis. These data, obtained after
controlled pollen exposure out of the pollen season, showed highly reproducible individual
responses prior to dosing. It is not clear, however, whether the same results can be obtained
during the pollen season, when additional natural pollen exposure may influence the
variability of the individual reactions.
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