CLINICAL TRIALS PROFILE FOR CITRIC ACID; MAGNESIUM OXIDE; SODIUM PICOSULFATE
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All Clinical Trials for citric acid; magnesium oxide; sodium picosulfate
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT02124447 ↗ | Single Center Comparison of 4 FDA Approved, Commercially Available Bowel Purgatives for Colonoscopy | Withdrawn | Medical College of Wisconsin | N/A | 2014-06-01 | This will be a 4-way comparison to prospectively evaluate the efficacy and patient tolerability of four commercially available bowel preparations among patients undergoing colonoscopy for screening and surveillance in a single tertiary academic medical center. |
| NCT03017235 ↗ | A Study Comparing the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution With PREPOPIK® for Colon Cleansing in Preparation for Colonoscopy | Completed | Ferring Pharmaceuticals | Phase 3 | 2017-02-20 | The purpose of this study is to compare the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution with PREPOPIK® for colon cleansing in adult subjects undergoing colonoscopy. |
| NCT03198221 ↗ | Comparison of Clenpiq vs Golytely Bowel Preparation | Terminated | Ferring Pharmaceuticals | Phase 4 | 2018-07-11 | This is a prospective randomized study which will be done at main campus Cleveland Clinic. The investigators will be comparing the colon cleansing by the Boston Bowel Preparation Scale in participants undergoing colonoscopy as an inpatient at our hospital. Participants will be randomized to the the standard of care (4 Liter polyethylene glycol based preparation) or a low volume bowel preparation (sodium picosulfate, a stimulant laxative, magnesium oxide and anhydrous citric acid (SP/MC)). Both agents will either be administered as full dose the evening before or as split-dose on the evening before and on the day of the procedure. |
| NCT03198221 ↗ | Comparison of Clenpiq vs Golytely Bowel Preparation | Terminated | The Cleveland Clinic | Phase 4 | 2018-07-11 | This is a prospective randomized study which will be done at main campus Cleveland Clinic. The investigators will be comparing the colon cleansing by the Boston Bowel Preparation Scale in participants undergoing colonoscopy as an inpatient at our hospital. Participants will be randomized to the the standard of care (4 Liter polyethylene glycol based preparation) or a low volume bowel preparation (sodium picosulfate, a stimulant laxative, magnesium oxide and anhydrous citric acid (SP/MC)). Both agents will either be administered as full dose the evening before or as split-dose on the evening before and on the day of the procedure. |
| NCT04161599 ↗ | Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial. | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | Phase 4 | 2021-09-14 | The ORALEV Study found that preoperative oral antibiotics can reduce the incidence of surgical site infections after colonic resection, compared with no preparation. The role of mechanical bowel preparation in patients needing colonic surgery is yet to be elucidated. No randomised controlled trials have assessed the impact of mechanical bowel preparation combined with oral antibiotics on the incidence of surgical site infections after colonic surgery, compared with oral antibiotics only. |
| NCT05148494 ↗ | TES RCT Fleet Enema vs Oral Mechanical Bowel Prep | Not yet recruiting | Nova Scotia Health Authority | Phase 4 | 2022-02-01 | There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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