Renal Safety Evaluation After Dotarem®-Enhanced MRI
Completed
Guerbet
Phase 4
2008-01-01
Although there is a well documented risk of acute renal failure with the iodinated contrast
agents, the implication of intravenous gadolinium-based contrast agents in nephrotoxicity
remains controversial. The aim of this study was to evaluate the safety profile of gadoterate
meglumine (Dotarem®) in patients with chronic renal insufficiency by evaluating the rate of
patients experiencing contrast-induced nephrotoxicity following the injection of gadoterate
meglumine.
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