CLINICAL TRIALS PROFILE FOR LIDOCAINE; PRILOCAINE
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All Clinical Trials for lidocaine; prilocaine
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00154167 ↗ | Safety and Efficacy Study of NV-101 in Dental Patients | Completed | Novalar Pharmaceuticals, Inc. | Phase 2 | 2003-02-01 | The purpose of this study was: - to determine if NV-101 accelerates recovery from numbness compared to placebo - to evaluate safety of NV-101 |
| NCT00355277 ↗ | Local Anaesthetic Effects of Transcutaneous Amitriptyline | Completed | University Hospital, Clermont-Ferrand | Phase 1 | 2005-11-01 | The aim of this study is to assess the local anaesthetic effects of amitriptyline applied on the skin of human volunteers, considering the differential effects on mechanic and thermic sensitivity, the local and general tolerance, and the systemic absorption of the drug. The solution used for dilution of amitriptyline is the only one known to allow transcutaneous absorption of the drug [1]. Considering that the peripheral sensitive fibre is a possible site of action of tricyclic antidepressants for relieving neuropathic pain [2,3], this is a first step study before further assessment of the therapeutic effects of transcutaneous amitriptyline. |
| NCT00483990 ↗ | Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers | Completed | Plethora Solutions Ltd | Phase 1 | 2007-03-01 | The main objective of the study is to determine the safety and tolerability of repeated application of PSD502 to the glans penis in healthy male volunteers |
| NCT00556478 ↗ | Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation | Completed | Shionogi Inc. | Phase 2/Phase 3 | 2007-10-01 | The purpose of this study is to evaluate the effectiveness, safety and tolerability of the investigational drug, PSD502 in subjects with premature ejaculation (PE) The study drug, PSD02, is a metered dose (measured dose), topical (applied to the skin surface) anesthetic (numbing) spray containing a mixture of lidocaine and prilocaine. The study drug will be applied in a spray to the penis prior to intercourse in order to decrease sensitivity in an attempt to delay ejaculation. |
| NCT00556478 ↗ | Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation | Completed | Plethora Solutions Ltd | Phase 2/Phase 3 | 2007-10-01 | The purpose of this study is to evaluate the effectiveness, safety and tolerability of the investigational drug, PSD502 in subjects with premature ejaculation (PE) The study drug, PSD02, is a metered dose (measured dose), topical (applied to the skin surface) anesthetic (numbing) spray containing a mixture of lidocaine and prilocaine. The study drug will be applied in a spray to the penis prior to intercourse in order to decrease sensitivity in an attempt to delay ejaculation. |
| NCT00808054 ↗ | Evaluation of Analgesia With EMLA and Glucose Oral Solution | Completed | Federal University of Minas Gerais | Phase 4 | 2008-11-01 | In this randomized controlled study the investigators intended to compare analgesic effects of EMLA and/or oral glucose in 60 preterm neonate during arterial function and PICC installation. |
| NCT00808171 ↗ | Evaluation of the Analgesy With Emla and/or Nitrous Oxide in Pediatric Patients for Lumbar Puncture | Completed | Federal University of Minas Gerais | Phase 4 | 2009-02-01 | In this randomised controlled study the investigators intended to compare the analgesic effects of EMLA and\or nitrous oxide in children submitted to lumbar puncture. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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