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Last Updated: November 17, 2024

CLINICAL TRIALS PROFILE FOR MOMELOTINIB DIHYDROCHLORIDE


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All Clinical Trials for momelotinib dihydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00935987 ↗ Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET) Completed Gilead Sciences Phase 1/Phase 2 2009-11-01 This study seeks to (i) determine a safe and tolerated dose of CYT387 (momelotinib) given to patients with PMF, post-PV or post-ET and, (ii) assess the effectiveness of orally-administered CYT387 as a treatment for PMF, post-PV or post-ET.
NCT00935987 ↗ Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET) Completed Sierra Oncology, Inc. Phase 1/Phase 2 2009-11-01 This study seeks to (i) determine a safe and tolerated dose of CYT387 (momelotinib) given to patients with PMF, post-PV or post-ET and, (ii) assess the effectiveness of orally-administered CYT387 as a treatment for PMF, post-PV or post-ET.
NCT01236638 ↗ Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET) Completed Gilead Sciences Phase 2 2010-11-01 This extension protocol to the core study CCL09101 allows patients who have tolerated the drug and derived a clinical benefit, to continue to receive treatment beyond the 9 cycles of the core protocol. Long term safety and efficacy of CYT387 (momelotinib) will be evaluated.
NCT01236638 ↗ Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET) Completed Sierra Oncology, Inc. Phase 2 2010-11-01 This extension protocol to the core study CCL09101 allows patients who have tolerated the drug and derived a clinical benefit, to continue to receive treatment beyond the 9 cycles of the core protocol. Long term safety and efficacy of CYT387 (momelotinib) will be evaluated.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for momelotinib dihydrochloride

Condition Name

Condition Name for momelotinib dihydrochloride
Intervention Trials
Primary Myelofibrosis 8
Post-essential Thrombocythemia Myelofibrosis 7
Post-Polycythemia Vera Myelofibrosis 6
Primary Myelofibrosis (PMF) 3
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Condition MeSH

Condition MeSH for momelotinib dihydrochloride
Intervention Trials
Primary Myelofibrosis 12
Polycythemia Vera 11
Polycythemia 11
Thrombocytosis 11
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Clinical Trial Locations for momelotinib dihydrochloride

Trials by Country

Trials by Country for momelotinib dihydrochloride
Location Trials
United States 125
Canada 32
France 22
Australia 20
Poland 19
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Trials by US State

Trials by US State for momelotinib dihydrochloride
Location Trials
California 15
Missouri 8
Texas 8
Florida 8
Arizona 8
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Clinical Trial Progress for momelotinib dihydrochloride

Clinical Trial Phase

Clinical Trial Phase for momelotinib dihydrochloride
Clinical Trial Phase Trials
Phase 3 5
Phase 2 7
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for momelotinib dihydrochloride
Clinical Trial Phase Trials
Completed 7
Terminated 5
Recruiting 3
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Clinical Trial Sponsors for momelotinib dihydrochloride

Sponsor Name

Sponsor Name for momelotinib dihydrochloride
Sponsor Trials
Sierra Oncology, Inc. 14
Gilead Sciences 13
PSI CRO 1
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Sponsor Type

Sponsor Type for momelotinib dihydrochloride
Sponsor Trials
Industry 32
NIH 2
Other 1
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