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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR PEGAPTANIB SODIUM


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All Clinical Trials for pegaptanib sodium

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00040313 ↗ Pegaptanib Sodium Compared to Sham Injection in Patients With DME Involving the Center of the Macula Completed Eyetech Pharmaceuticals Phase 2 2002-10-01 The purpose of the study is to determine whether pegaptanib sodium (Macugen) is safe and effective in slowing the leakage of fluid within the retina and thereby stabilizing or improving vision when compared to placebo injections. A total of 176 patients will be enrolled
NCT00087763 ↗ Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD) Completed Pfizer Phase 2 2004-03-01 The purpose of this study is to determine if Macugen™ reduces foveal thickness and improves vision in patients with wet AMD.
NCT00087763 ↗ Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD) Completed Eyetech Pharmaceuticals Phase 2 2004-03-01 The purpose of this study is to determine if Macugen™ reduces foveal thickness and improves vision in patients with wet AMD.
NCT00088192 ↗ Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD) Completed Pfizer N/A 2004-07-01 To provide Pegaptanib sodium injection to patients with subfoveal choroidal neovascularization (CNV) secondary to AMD, who are unable to participate in any of the Sponsor's other clinical studies with this drug for AMD, until such time as the patient's lesion is considered to have resolved or stabilized in the opinion of the treating ophthalmologist, or product becomes commercially available.
NCT00088192 ↗ Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD) Completed Eyetech Pharmaceuticals N/A 2004-07-01 To provide Pegaptanib sodium injection to patients with subfoveal choroidal neovascularization (CNV) secondary to AMD, who are unable to participate in any of the Sponsor's other clinical studies with this drug for AMD, until such time as the patient's lesion is considered to have resolved or stabilized in the opinion of the treating ophthalmologist, or product becomes commercially available.
NCT00088283 ↗ Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) Completed Pfizer Phase 2 2004-05-01 Eyetech Pharmaceuticals Inc. and Pfizer, Inc. are studying an investigational drug, MacugenTM, for the possible treatment of CRVO. An investigational drug is one that has not been approved by the U.S. Food and Drug Administration (FDA). This investigational drug may slow the growth of abnormal blood vessels in the eye and may reduce tissue swelling in the eye. The purpose of this study is to compare the safety and efficacy of a Macugen™ injection to a "pretend" injection. In addition, the purpose of this study is to measure the action of the study drug in the body over a period of time and to check for the presence of the study drug in your blood (called pharmacokinetics or PK). This study will involve approximately 90 people. People who decide to participate will have an equal chance (1 in 3) to receive one of three study injections, two of which are Macugen™ and one of which is a "pretend" injection.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for pegaptanib sodium

Condition Name

Condition Name for pegaptanib sodium
Intervention Trials
Macular Degeneration 8
Diabetic Macular Edema 5
Age-Related Macular Degeneration 5
Neovascular Age-related Macular Degeneration 3
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Condition MeSH

Condition MeSH for pegaptanib sodium
Intervention Trials
Macular Degeneration 17
Macular Edema 11
Edema 7
Retinal Diseases 6
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Clinical Trial Locations for pegaptanib sodium

Trials by Country

Trials by Country for pegaptanib sodium
Location Trials
United States 91
Japan 38
France 6
Canada 4
Spain 4
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Trials by US State

Trials by US State for pegaptanib sodium
Location Trials
Texas 9
California 7
Florida 6
Michigan 5
Massachusetts 5
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Clinical Trial Progress for pegaptanib sodium

Clinical Trial Phase

Clinical Trial Phase for pegaptanib sodium
Clinical Trial Phase Trials
Phase 4 7
Phase 3 4
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for pegaptanib sodium
Clinical Trial Phase Trials
Completed 22
Terminated 6
Withdrawn 3
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Clinical Trial Sponsors for pegaptanib sodium

Sponsor Name

Sponsor Name for pegaptanib sodium
Sponsor Trials
Pfizer 20
Eyetech Pharmaceuticals 11
Postgraduate Institute of Medical Education and Research 2
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Sponsor Type

Sponsor Type for pegaptanib sodium
Sponsor Trials
Industry 34
Other 15
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