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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR TIPIRACIL HYDROCHLORIDE; TRIFLURIDINE

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All Clinical Trials for tipiracil hydrochloride; trifluridine

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01955837 ↗	Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in Asia	Completed	Taiho Pharmaceutical Co., Ltd.	Phase 3	2013-09-01	To compare the effects of TAS-102 with placebo in patients with metastatic colorectal cancer refractory or intolerable to standard chemotherapies.
NCT02654639 ↗	Ph 2 Study of TAS-102 / Bevacizumab Maintenance Therapy Post Induction Chemotherapy in Metastatic Colorectal Cancer	Terminated	Georgetown University	Phase 2	2016-02-01	Phase II study of TAS-102 plus bevacizumab switch maintenance therapy in patients with mCRC
NCT03278106 ↗	TAS-102 in Treating Advanced Biliary Tract Cancers	Active, not recruiting	National Cancer Institute (NCI)	Phase 2	2017-10-20	This phase II trial studies how well trifluridine/tipiracil hydrochloride combination agent TAS-102 (TAS-102) works in treating participants with biliary tract cancers that have spread to other places in the body. Drugs used in the chemotherapy, such as trifluridine/tipiracil hydrochloride combination agent TAS-102, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
NCT03278106 ↗	TAS-102 in Treating Advanced Biliary Tract Cancers	Active, not recruiting	Mayo Clinic	Phase 2	2017-10-20	This phase II trial studies how well trifluridine/tipiracil hydrochloride combination agent TAS-102 (TAS-102) works in treating participants with biliary tract cancers that have spread to other places in the body. Drugs used in the chemotherapy, such as trifluridine/tipiracil hydrochloride combination agent TAS-102, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for tipiracil hydrochloride; trifluridine

Condition Name

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Condition Name for tipiracil hydrochloride; trifluridine
Intervention	Trials
Metastatic Colorectal Cancer	12
Colorectal Cancer	7
Stage IVC Colorectal Cancer AJCC v8	6
Stage IV Colorectal Cancer AJCC v8	6
[disabled in preview]	0
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Condition MeSH

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Condition MeSH for tipiracil hydrochloride; trifluridine
Intervention	Trials
Colorectal Neoplasms	39
Adenocarcinoma	17
Colonic Neoplasms	8
Carcinoma	8
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Clinical Trial Locations for tipiracil hydrochloride; trifluridine

Trials by Country

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Trials by Country for tipiracil hydrochloride; trifluridine
Location	Trials
United States	111
Italy	28
China	25
Japan	18
Australia	11
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Trials by US State

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Trials by US State for tipiracil hydrochloride; trifluridine
Location	Trials
California	10
Florida	8
Texas	8
Minnesota	8
Arizona	8
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Clinical Trial Progress for tipiracil hydrochloride; trifluridine

Clinical Trial Phase

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Clinical Trial Phase for tipiracil hydrochloride; trifluridine
Clinical Trial Phase	Trials
Phase 3	11
Phase 2	33
Phase 1/Phase 2	5
[disabled in preview]	8
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Clinical Trial Status

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Clinical Trial Status for tipiracil hydrochloride; trifluridine
Clinical Trial Phase	Trials
Recruiting	27
Not yet recruiting	14
Active, not recruiting	6
[disabled in preview]	3
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Clinical Trial Sponsors for tipiracil hydrochloride; trifluridine

Sponsor Name

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Sponsor Name for tipiracil hydrochloride; trifluridine
Sponsor	Trials
National Cancer Institute (NCI)	14
Servier	4
Mayo Clinic	4
[disabled in preview]	4
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Sponsor Type

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Sponsor Type for tipiracil hydrochloride; trifluridine
Sponsor	Trials
Other	55
Industry	30
NIH	14
[disabled in preview]	0
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