Drug Price Trends for OXYCODONE-ACETAMINOPHEN

Average Pharmacy Cost for OXYCODONE-ACETAMINOPHEN

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	42858-0104-50	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	00406-0523-62	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	42858-0104-01	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	00406-0523-01	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	13107-0046-01	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	00406-0523-05	0.21817	EACH	2024-12-18
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB	00406-0523-23	0.21817	EACH	2024-12-18

OXYCODONE-ACETAMINOPHEN Market Analysis and Financial Projection

Market Analysis and Price Projections for Oxycodone-Acetaminophen

Market Overview

The global market for acetaminophen-opioid combination drugs, including oxycodone-acetaminophen, is experiencing significant growth driven by several key factors.

Increasing Prevalence of Cancer and Pain Management

The rising prevalence of cancer and the associated need for effective pain management are major drivers of this market. Cancer-related pain, which can be caused by the cancer itself or by treatments such as chemotherapy and radiation, is a common symptom that necessitates the use of potent pain relievers like oxycodone-acetaminophen[1].

Market Size and Growth

The global acetaminophen-opioid combination market is projected to grow from USD 3,144.1 million in 2024 to USD 4,522.6 million by 2034, at a compound annual growth rate (CAGR) of 3.7%. This growth is largely attributed to the increasing demand for effective pain management solutions[1].

Product Segments and Market Share

By Product

The hydrocodone-acetaminophen segment holds a significant market share, with 49.8% in 2023, due to the wide availability of products containing this combination. However, oxycodone-acetaminophen is also a prominent segment, particularly in regions like North America[1].

By Indication

Acute pain management dominates the market, with a share of 58.3% in 2023. This is due to the high prevalence of acute pain, the increasing incidence of surgeries and injuries, and the shorter treatment duration which reduces the risk of opioid addiction[1].

By Strength

Moderate to high dose combinations of acetaminophen-opioid, including oxycodone-acetaminophen, dominate the market with a 45.6% share in 2023. These combinations are widely used for their potent pain relief capabilities[1].

Distribution Channels

Hospital Pharmacies

Hospital pharmacies hold a significant share of 39.9% in 2023, primarily because opioids are highly regulated and require proper prescription and medical supervision. This ensures that these medications are mostly administered within healthcare facilities[1].

Regional Analysis

North America

North America is the leading region, accounting for 43.5% of the market share by the end of the forecast period. This is due to the increasing adoption of acetaminophen-opioid combinations and the presence of a large number of manufacturers in the region[1].

Pricing and Cost Analysis

Retail Prices

The retail prices of oxycodone-acetaminophen vary widely depending on the dosage, quantity, and pharmacy. For example, a supply of 30 tablets of 325 mg-10 mg oxycodone-acetaminophen can cost around $15, while larger quantities or different dosages can range from $17 to over $1,600 for specific formulations[2][5].

Cost-Effectiveness

From a cost-effectiveness perspective, studies have shown mixed results. For instance, an economic evaluation comparing controlled-release oxycodone with oxycodone-acetaminophen found that oxycodone was more effective and less costly from a societal perspective. However, from a healthcare system perspective, the cost-effectiveness varied, with oxycodone being more costly but also more effective in some scenarios[4].

Future Trends and Projections

Personalized Pain Management

Advances in pharmacogenomics are expected to drive more personalized pain management strategies, which could lead to more targeted and effective use of oxycodone-acetaminophen combinations. This trend is likely to enhance the safety and efficacy of these medications, further boosting their adoption[1].

Multimodal Pain Management

Growing awareness of multimodal pain management methods and the emergence of opioid-based precision medicine are also key factors that will influence the market. These approaches aim to reduce the risk of opioid addiction while providing effective pain relief[1].

Regulatory and Public Health Considerations

Opioid Misuse and Regulation

The rise in overdose deaths from prescription opioids has led to increased regulatory scrutiny and public health initiatives aimed at curbing opioid misuse. This includes proposals for price changes and stricter prescription guidelines, which can impact the demand for pain relief drugs like oxycodone-acetaminophen[3].

Key Takeaways

• Market Growth: The global acetaminophen-opioid combination market, including oxycodone-acetaminophen, is projected to grow significantly, driven by increasing cancer prevalence and the need for effective pain management.
• Product Segments: Hydrocodone-acetaminophen and oxycodone-acetaminophen are key segments, with moderate to high dose combinations dominating the market.
• Distribution: Hospital pharmacies play a crucial role due to the regulated nature of opioids.
• Regional Dominance: North America leads the market due to high adoption rates and the presence of numerous manufacturers.
• Pricing: Prices vary widely based on dosage and quantity, with cost-effectiveness analyses showing mixed results.
• Future Trends: Personalized pain management and multimodal approaches are expected to drive market growth and improve safety and efficacy.

FAQs

1. What is driving the growth of the acetaminophen-opioid combination market? The growth is primarily driven by the increasing prevalence of cancer and the associated need for effective pain management.

2. Which segment holds the largest market share in the acetaminophen-opioid combination market? The hydrocodone-acetaminophen segment holds the largest market share, but oxycodone-acetaminophen is also a significant segment.

3. How do hospital pharmacies influence the distribution of oxycodone-acetaminophen? Hospital pharmacies hold a significant share due to the regulated nature of opioids, ensuring these medications are administered under proper medical supervision.

4. What are the future trends expected to impact the oxycodone-acetaminophen market? Advances in pharmacogenomics and the adoption of multimodal pain management methods are expected to drive more personalized and effective pain management strategies.

5. How do regulatory measures impact the demand for oxycodone-acetaminophen? Regulatory measures aimed at curbing opioid misuse, such as price changes and stricter prescription guidelines, can influence the demand for these medications.

Sources

1. Global Acetaminophen-Opioid Combination Market Growth - GlobeNewswire
2. Acetaminophen/oxycodone Prices, Coupons, Copay Cards - Drugs.com
3. Health Insurance, Price Changes, and the Demand for Pain Relief Drugs - Kelley School of Business
4. Economic Evaluation of Controlled-release Oxycodone vs Oxycodone-Acetaminophen - American Journal of Managed Care
5. Oxycodone-Acetaminophen Coupons & Prices - SingleCare