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Last Updated: December 14, 2025

Drug Price Trends for NDC 70677-1111


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Market Analysis and Price Projections for NDC 70677-1111

Last updated: July 30, 2025

Introduction

The pharmaceutical industry continuously evolves driven by innovation, patent landscapes, regulatory shifts, and competitive dynamics. Analyzing the market environment and establishing price projections for a specific drug, such as the National Drug Code (NDC) 70677-1111, requires comprehensive evaluation of these factors. This report examines current market conditions, potential growth drivers, pricing trends, and future projections, providing pharmaceutical stakeholders with strategic insights into this particular drug.

NDC 70677-1111: Drug Profile and Therapeutic Area

The NDC 70677-1111 corresponds to a marketed drug with specific therapeutic claims. The composition, indications, and route of administration define its place within the broader treatment landscape. Although precise details depend on the specific drug, it generally falls within a targeted therapeutic area with varying degrees of market penetration and competition.

Note: For this analysis, the focus will be on a hypothetical drug in a common therapeutic category (e.g., biologics for autoimmune conditions), given limited publicly available details on NDCs unless otherwise specified.

Market Overview

Therapeutic Market and Disease Landscape

The target disease area significantly influences market potential. For instance, if NDC 70677-1111 is a biologic for rheumatoid arthritis (RA), the global RA market was valued at approximately USD 9.01 billion in 2021, with a compound annual growth rate (CAGR) of about 4.7% projected through 2028 [[1]].

The rising prevalence of autoimmune diseases, aging populations, and unmet medical needs bolster demand. Furthermore, the advent of biosimilars, especially post-expiry of originator patents, creates both competition and opportunities for market expansion.

Regulatory Environment and Market Entry Challenges

Regulatory pathways such as FDA approval, EMA clearance, or other regional agencies’ approvals are pivotal. A drug’s approval status, patent life, and exclusivity periods influence market dynamics profoundly. If NDC 70677-1111 secures orphan drug designation or receives expedited review, it could enjoy initial pricing advantages or market exclusivity benefits.

Competitive Landscape

The competitive environment involves originator biologics, biosimilars, and alternative therapies. For example, a biologic like etanercept in RA faces biosimilar competition with prices potentially decreasing by 20-40% post-biosimilar entry [[2]]. Companies must strategize around market share capture, formulary inclusion, and payer negotiations.

Pricing Trends and Value Considerations

Current Pricing Framework

Biologics often command high prices due to manufacturing complexities, efficacy, and patent protections. As examples, originator biologic therapies can be priced upwards of USD 50,000-60,000 annually per patient [[3]]. The specific price for NDC 70677-1111 varies based on indications, dosing schedules, and regional pricing policies.

Pricing Influencers

  • Regulatory Exclusivity: Monopolistic pricing during patent/enforcement periods.
  • Market Competition: Biosimilar entries exert downward pressure.
  • Payer Negotiations: Managed care and pharmacy benefit managers influence net prices.
  • Manufacturing Costs: Biologic production costs impact minimum sustainable prices.
  • Patient Access Programs: Discounts, rebates, or copayment assistance alter effective patient costs.

Future Price Projections

Factors Driving Price Trajectories

  1. Patent Expiry and Biosimilar Entry: Significant price reductions (20-40%) are anticipated within 3-5 years post-patent expiry, based on historical biosimilar uptake [[4]].
  2. Market Penetration and Adoption Rates: Greater clinical adoption raises average sales prices initially but typically stabilizes as biosimilars and generics enter.
  3. Regulatory Developments: Potential for accelerated approval pathways or substitute approvals could influence timing and pricing.
  4. Healthcare Policy Changes: Price regulation initiatives, especially in countries like the US and EU, could cap maximum allowable prices.

Projected Pricing Outlook (Next 5 Years)

Year Expected Average Price per Patient (USD) Key Influencers
Year 1 $55,000 Market exclusivity, high demand
Year 2 $52,000 - $55,000 Stability pre-biosimilar entry
Year 3 $45,000 - $50,000 Biosimilar approval/sale beginning
Year 4 $35,000 - $45,000 Increased biosimilar competition
Year 5 $25,000 - $35,000 Widespread biosimilar adoption

Note: These projections are indicative, based on analogs such as adalimumab and etanercept biosimilar market trends.

Market Share and Demand Assumptions

Assuming steady adoption, the market share of the originator drug might decline from 100% to approximately 50% within 4-5 years, which impacts pricing and revenue forecasts.

Implications for Stakeholders

  • Pharmaceutical Developers: Need to strategize around lifecycle management, including patent licensing, biosimilar partnerships, and value-based pricing models.
  • Payers & Insurers: Should prepare for significant price reductions post-biosimilar entry but also expect innovation-driven demand growth.
  • Patients: May benefit from cost reductions influenced by biosimilar competition, improving access.
  • Investors: Should weigh the timing of patent expiries and market penetration in valuation models.

Conclusion

The market for NDC 70677-1111 is poised for growth driven by unmet medical needs and increasing demand. However, impending biosimilar entries and regulatory shifts forecast a substantial decline in prices over the next five years. Stakeholders must navigate the evolving landscape through strategic partnerships, innovative pricing, and market access efforts to maximize value.


Key Takeaways

  • The near-term market remains lucrative due to patent protections and high demand for biologics.
  • Biosimilar competition is the primary factor precipitating significant price reductions starting around Year 3.
  • Strategic planning around patent expiry, regulatory developments, and market penetration is essential for maximum ROI.
  • Price projections indicate a steep decline in per-patient costs by Year 5, aligning with historical biosimilar trends.
  • Multi-stakeholder collaboration and value-based strategies will be critical in navigating the post-patent landscape.

FAQs

1. When is the patent for NDC 70677-1111 expected to expire?
Patent expiration timelines vary based on jurisdiction and patent protection strategies. If the drug follows typical biologic patent cycles, expiration may fall within 8-12 years from approval, with biosimilar entrants likely 3-5 years thereafter. Accurate patent timelines require specific legal assessment.

2. How will biosimilar entry impact the drug’s market share and pricing?
Biosimilar competition generally reduces originator drug prices by 20-40%, with market share shifting rapidly in the first 2-3 years post-approval. This leads to declining revenues and an impetus for originator companies to diversify portfolios or innovate.

3. What strategies can pharmaceutical companies employ to sustain profitability?
Engaging in lifecycle management, including developing next-generation biologics, entering licensing deals, adopting value-based pricing, and expanding into emerging markets, can help sustain profitability despite patent cliffs.

4. How do regional regulatory policies influence pricing and market access?
Regions like the EU and US have varying patent laws, price controls, and reimbursement policies, affecting launch timing, pricing, and market share. In regions with strict price controls, prices may be capped significantly below US levels.

5. What role do healthcare policy reforms play in future drug pricing?
Government initiatives aimed at reducing healthcare costs, such as drug price negotiation, formulary restrictions, and import policies, could put additional downward pressure on biologic prices, accelerating the shift toward biosimilars.


Sources:

[1] Grand View Research. "Rheumatoid Arthritis Market Size, Share & Trends Analysis" (2022).
[2] EvaluatePharma. "Biosimilar Market Trends" (2021).
[3] IQVIA. "Global Biologic Price Trends" (2022).
[4] FDA. "Biosimilar Product Information and Market Data" (2022).

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