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Calcium chloride - Generic Drug Details

What are the generic sources for calcium chloride and what is the scope of patent protection?

Calcium chloride is the generic ingredient in one hundred and one branded drugs marketed by Amneal, Am Regent, Intl Medication Sys, Medefil Inc, Hospira, Alcon, Epic Pharma Llc, Baxter Hlthcare Corp, Alcon Pharms Ltd, B Braun, Baxter Hlthcare, Fresenius Medcl, Fresenius, Lukare Medical Llc, Fresenius Kabi Usa, Icu Medical Inc, Miles, and Abbott, and is included in seventy-two NDAs. Additional information is available in the individual branded drug profile pages.

There are four drug master file entries for calcium chloride. Ten suppliers are listed for this compound.

Summary for calcium chloride

US Patents:	0
Tradenames:	101
Applicants:	18
NDAs:	72
Drug Master File Entries:	4
Finished Product Suppliers / Packagers:	10
Raw Ingredient (Bulk) Api Vendors:	99
Patent Applications:	4,399
Drug Prices:	Drug price trends for calcium chloride
What excipients (inactive ingredients) are in calcium chloride?	calcium chloride excipients list
DailyMed Link:	calcium chloride at DailyMed

See drug prices for calcium chloride

Pharmacology for calcium chloride

Drug Class	Blood Coagulation Factor Phosphate Binder
Mechanism of Action	Phosphate Chelating Activity
Physiological Effect	Increased Coagulation Factor Activity

Anatomical Therapeutic Chemical (ATC) Classes for calcium chloride

A12AA	Calcium
A12A	CALCIUM
A12	MINERAL SUPPLEMENTS
A	Alimentary tract and metabolism

B05XA	Electrolyte solutions
B05X	I.V. SOLUTION ADDITIVES
B05	BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B	Blood and blood forming organs

G04BA	Acidifiers
G04B	UROLOGICALS
G04	UROLOGICALS
G	Genito-urinary system and sex hormones

US Patents and Regulatory Information for calcium chloride

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Alcon	BSS	calcium chloride; magnesium chloride; potassium chloride; sodium acetate; sodium chloride; sodium citrate	SOLUTION;IRRIGATION	020742-001	Dec 10, 1997	AT	RX	Yes	Yes
Baxter Hlthcare Corp	PRISMASOL BGK 4/0 IN PLASTIC CONTAINER	calcium chloride; dextrose; lactic acid; magnesium chloride; potassium chloride; sodium bicarbonate; sodium chloride	INJECTABLE;INJECTION	021703-005	Oct 25, 2006		DISCN	No	No
Baxter Hlthcare	RINGER'S IN PLASTIC CONTAINER	calcium chloride; potassium chloride; sodium chloride	SOLUTION;IRRIGATION	018495-001	Feb 19, 1982	AT	RX	No	No
Icu Medical Inc	POTASSIUM CHLORIDE 10MEQ IN DEXTROSE 5% AND LACTATED RINGER'S IN PLASTIC CONTAINER	calcium chloride; dextrose; potassium chloride; sodium chloride; sodium lactate	INJECTABLE;INJECTION	019685-006	Oct 17, 1988		DISCN	Yes	No
B Braun	DEXTROSE 2.5% IN HALF-STRENGTH LACTATED RINGER'S IN PLASTIC CONTAINER	calcium chloride; dextrose; potassium chloride; sodium chloride; sodium lactate	INJECTABLE;INJECTION	019634-001	Feb 24, 1988		RX	No	No
Baxter Hlthcare	DIANEAL PD-1 W/ DEXTROSE 2.5% IN PLASTIC CONTAINER	calcium chloride; dextrose; magnesium chloride; sodium chloride; sodium lactate	SOLUTION;INTRAPERITONEAL	017512-008	Jul 9, 1984		DISCN	No	No

Calcium chloride Market Analysis and Financial Projection Experimental

Calcium Chloride Market Dynamics and Financial Trajectory

Market Overview

The calcium chloride market is poised for significant growth, driven by its diverse and critical applications across various industries. Here are the key dynamics and financial trends shaping this market.

Market Size and Growth

The calcium chloride market was valued at USD 1.7 billion in 2023 and is projected to reach USD 2.3 billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.41%[1].

Industrial Applications and Demand

Calcium chloride's versatility in industrial applications is a major driver of its market growth. It is used as a key ingredient in the production of chemicals like calcium carbonate and calcium hypochlorite. Its roles as a catalyst and desiccant in chemical reactions enhance product quality and efficiency, increasing demand. In the polymer production, pulp and paper treatment, moisture absorption, and mining operations, calcium chloride plays a crucial role, further solidifying its industrial relevance[1].

Construction and Concrete Industry

The growth of the construction and concrete industries, particularly in urbanizing regions like India and China, presents significant opportunities for the calcium chloride market. Calcium chloride is widely used as an accelerator in concrete mixtures, enhancing the curing process and reducing setting times. This is especially beneficial in cold climates, where it accelerates project completion and reduces overall costs[1].

Regional Insights

North America

North America dominates the calcium chloride market, with the United States and Canada being key contributors. The region's construction industry drives demand, particularly for de-icing and road maintenance. In 2024, prices in the U.S. increased due to high demand from the construction sector and rising raw material costs, such as calcium carbonate[1][2][5].

Europe

In Europe, the calcium chloride market has faced challenges due to lower cost support from its feedstock, calcium carbonate, and disruptions in the shipping industry. Despite these challenges, the construction sector's demand has persisted, though rising costs for raw materials and freight have impacted pricing dynamics[2].

Asia

Asian countries, particularly India, have seen stable demand for calcium chloride, though this has been affected by factors such as the fall in raw material costs and surplus supply. Indian companies like Tata Chemicals have experienced declines in profits due to weak demand and surplus supply[2].

Price Trends

Current Pricing

As of the end of 2023, the price of calcium chloride in the U.S. was around USD 300 per metric ton, while in Europe it was approximately USD 200 per metric ton[2].

Future Outlook

The price trend of calcium chloride is expected to mirror the sentiments of its feedstock commodities, such as hydrochloric acid and calcium carbonate. Despite stable demand from the construction industry, rising raw material costs and supply chain challenges are likely to maintain upward pressure on prices. In the U.S., prices are expected to rise further due to increasing production costs linked to raw material prices[2][5].

Supply and Demand Dynamics

Supply Chain

Domestic production in the U.S. has remained stable, with manufacturing plants operating at optimum capacity. However, supply chain challenges, including low inventory levels and disruptions in the shipping industry, have impacted the market. Inventory levels are gradually replenishing to meet increasing downstream demand, but the ongoing rise in production expenses continues to influence market dynamics[2][5].

Demand Drivers

Demand for calcium chloride remains strong, driven by its widespread applications in construction, de-icing, and other industrial sectors. The construction sector's growth, particularly in residential and nonbuilding projects, is a significant driver of this demand. Economic improvements, such as potential interest rate cuts, may further boost demand in the coming months[1][5].

Economic and Regulatory Factors

Economic Impact

The economic environment, including interest rate changes and inflation, significantly affects the calcium chloride market. For instance, the European Central Bank's interest rate cut initially supported positive market sentiment and boosted economic activity, increasing demand for calcium chloride. However, rising import prices and shipping disruptions have complicated the market outlook[2].

Regulatory and Sustainability Requirements

Regulatory and sustainability requirements, especially in regions like the Netherlands, add to the cost pressures in the calcium chloride market. These requirements can impact production costs and pricing dynamics, making it essential for manufacturers to balance compliance with market demands[2].

Key Players and Market Segmentation

The global calcium chloride market is segmented into food grade, pharmaceutical grade, agricultural grade, and industrial grade. Key players in the market are leveraging these segments to cater to diverse industry needs. For example, the pharmaceutical and medical sectors in Europe are driving demand for specific grades of calcium chloride[4].

Analyst Insights

Analysts predict that the calcium chloride market will continue to grow, driven by stable and consistent demand from the construction industry and other downstream sectors. However, growing economic concerns and trading challenges might hinder the upward movement of calcium chloride prices. The market's trajectory will closely follow the dynamics of its feedstock materials and the overall economic environment[2].

Conclusion

The calcium chloride market is poised for growth, driven by its critical roles in various industries, particularly construction and chemical production. While supply chain challenges and rising raw material costs present short-term hurdles, the long-term outlook remains positive due to sustained demand and expanding applications.

Key Takeaways

• Market Growth: The calcium chloride market is expected to grow from USD 1.7 billion in 2023 to USD 2.3 billion by 2030 at a CAGR of 4.41%.
• Industrial Applications: Calcium chloride's use in chemical production, polymer manufacturing, and construction drives its demand.
• Regional Dominance: North America, led by the U.S. and Canada, dominates the market due to high demand from the construction sector.
• Price Trends: Prices are expected to rise due to increasing raw material costs and supply chain challenges.
• Demand Drivers: Construction sector growth and economic improvements are key drivers of demand.

FAQs

Q: What is the current market size of the calcium chloride market? A: The calcium chloride market was valued at USD 1.7 billion in 2023[1].

Q: What is the expected CAGR of the calcium chloride market from 2023 to 2030? A: The market is expected to grow at a CAGR of 4.41% from 2023 to 2030[1].

Q: Which region dominates the calcium chloride market? A: North America, particularly the U.S. and Canada, dominates the market[1][2][4].

Q: What are the primary drivers of demand for calcium chloride? A: The primary drivers include its use in the construction sector, chemical production, and other industrial applications[1][5].

Q: How do supply chain challenges affect the calcium chloride market? A: Supply chain challenges, such as low inventory levels and shipping disruptions, impact pricing dynamics and market stability[2][5].

Sources

1. Maximize Market Research: Calcium Chloride Market: Size, Dynamics, Regional Insights.
2. Procurement Resource: Calcium Chloride Price Trend, Index, News, Chart, Database.
3. Cognitive Market Research: Calcium Chloride CaCl2 Market Report 2024 (Global Edition).
4. Fortune Business Insights: Calcium Chloride Market Size, Share, & Forecast, 2032.
5. ChemAnalyst: Expensive Feedstock Affects US Calcium Chloride Prices, Consumption Outlooks Seems Promising.