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Last Updated: December 22, 2024

Cocaine hydrochloride - Generic Drug Details


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What are the generic sources for cocaine hydrochloride and what is the scope of freedom to operate?

Cocaine hydrochloride is the generic ingredient in two branded drugs marketed by Noden Pharma and Omnivium Pharms, and is included in two NDAs. There are twelve patents protecting this compound. Additional information is available in the individual branded drug profile pages.

There are three drug master file entries for cocaine hydrochloride. Three suppliers are listed for this compound.

DrugPatentWatch® Estimated Loss of Exclusivity (LOE) Date for cocaine hydrochloride
Generic Entry Dates for cocaine hydrochloride*:
Constraining patent/regulatory exclusivity:
Dosage:
SOLUTION;NASAL
Generic Entry Dates for cocaine hydrochloride*:
Constraining patent/regulatory exclusivity:
Dosage:
SOLUTION;NASAL

*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

Recent Clinical Trials for cocaine hydrochloride

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
University of California, Los AngelesEarly Phase 1
Spaulding Rehabilitation HospitalEarly Phase 1
Multidisciplinary Association for Psychedelic StudiesEarly Phase 1

See all cocaine hydrochloride clinical trials

Medical Subject Heading (MeSH) Categories for cocaine hydrochloride

US Patents and Regulatory Information for cocaine hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Noden Pharma GOPRELTO cocaine hydrochloride SOLUTION;NASAL 209963-001 Dec 14, 2017 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Noden Pharma GOPRELTO cocaine hydrochloride SOLUTION;NASAL 209963-001 Dec 14, 2017 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Omnivium Pharms NUMBRINO cocaine hydrochloride SOLUTION;NASAL 209575-001 Jan 10, 2020 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Noden Pharma GOPRELTO cocaine hydrochloride SOLUTION;NASAL 209963-001 Dec 14, 2017 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Omnivium Pharms NUMBRINO cocaine hydrochloride SOLUTION;NASAL 209575-001 Jan 10, 2020 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Omnivium Pharms NUMBRINO cocaine hydrochloride SOLUTION;NASAL 209575-001 Jan 10, 2020 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Cocaine hydrochloride Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Cocaine Hydrochloride

Introduction

Cocaine hydrochloride, a highly addictive and illicit substance, has seen significant fluctuations in its market dynamics over the years. This article delves into the current state of cocaine hydrochloride production, its financial trajectory, and the factors influencing its market.

Global Production Trends

In recent years, the production of cocaine hydrochloride has reached all-time highs. By 2019, global production was estimated to be around 1,784 tonnes, primarily driven by increased production in Colombia[1][5].

  • Colombia's Dominance: Colombia remains the largest producer of cocaine hydrochloride. In 2020, despite initial disruptions due to the COVID-19 pandemic, Colombia's production increased to an estimated 1,228 tonnes, a 10% rise from 2019 and a 233% increase from 2014[1].
  • Other Producing Countries: Bolivia and Peru also saw an increase in coca cultivation in 2020, contributing to the overall rise in global production[1].

Impact of COVID-19

The COVID-19 pandemic had a temporary but significant impact on the cocaine market.

  • Price Fluctuations: There was a reported drop in the price of coca leaves in Colombia and Peru during the early stages of the pandemic. Additionally, cocaine production in Colombia was disrupted due to fuel shortages[1].
  • Recovery and Growth: Despite these initial disruptions, the market quickly recovered, and production continued to rise, indicating the resilience of the illicit cocaine trade[1].

Efficiency in Manufacturing

The efficiency of cocaine manufacturing processes has been on the rise.

  • Technological Advancements: The trend towards more efficient cocaine manufacturing, noted in previous reports, continues to gain strength. This has led to higher production capacities and better yield from coca bush cultivation[1].
  • Large-Scale Operations: Law enforcement actions in Europe, such as the dismantling of secondary extraction facilities in Spain and the Netherlands, have revealed that cocaine hydrochloride manufacturing activities are more extensive than previously thought. For example, some facilities in the Netherlands had production capacities of between 100 and 200 kilograms per day[1].

Demand and Supply Dynamics

The demand for cocaine hydrochloride is closely tied to its supply.

  • Elastic Demand: Research indicates that the global demand for cocaine is elastic and follows the law of demand. As income increases, so does the demand for cocaine, making it a normal good in economic terms[4].
  • Regional Variations: The UNODC Global Report on Cocaine 2023 highlights a significant increase in coca cultivation and cocaine production, which has been matched by a rise in demand. The Americas and parts of Europe remain the primary markets, but there is a growing potential for expansion in Africa and Asia[5].

Economic Model and Regulation

From an economic perspective, the cocaine market operates under imperfect competition.

  • Internal Economies of Scale: The production of cocaine exhibits internal economies of scale, meaning that larger producers can reduce their costs per unit. This has implications for the regulation of the market, suggesting that efficient regulation would need to consider these economies of scale[4].
  • Price Regulation: Efficient regulation of the cocaine market would involve setting prices within a legal context to manage both production and consumption effectively[4].

Financial Trajectory

The financial aspects of the cocaine hydrochloride market are complex and influenced by various factors.

  • Revenue Streams: The illicit nature of the cocaine trade makes it difficult to estimate exact revenue figures. However, the large-scale production and distribution operations indicate significant financial flows. For instance, the dismantling of large-scale manufacturing facilities suggests substantial investment and revenue generation[1].
  • Cost Structure: The cost structure of cocaine production includes the cost of coca leaves, fuel, and other inputs. The efficiency gains in manufacturing processes have likely reduced these costs, making the production more profitable[1].

Market Segmentation and Target Audiences

The market for cocaine hydrochloride and its derivatives, such as crack cocaine, is segmented based on various factors.

  • Powder Cocaine vs. Crack Cocaine: Powder cocaine, or cocaine hydrochloride, is often associated with a different demographic compared to crack cocaine. Powder cocaine is more commonly used by students and professionals seeking to enhance performance, while crack cocaine is more frequently linked to poverty and targeted by dealers towards heroin addicts[2].

Law Enforcement Efforts

Law enforcement actions play a crucial role in disrupting the cocaine market.

  • Seizures and Dismantling Operations: Record-high seizures of nearly 2,000 tons in 2021 indicate increased efforts by law enforcement to curb the supply of cocaine. The dismantling of large-scale manufacturing facilities in Europe further underscores these efforts[1][5].

Future Outlook

The future of the cocaine hydrochloride market is marked by several trends and challenges.

  • Expansion into New Markets: There is a strong potential for the cocaine market to expand into Africa and Asia, driven by growing demand and improvements in production processes[5].
  • Regulatory Challenges: Efficient regulation of the market remains a challenge. The economic model suggests that regulating the market through price mechanisms within a legal context could be effective, but this is complicated by the illicit nature of the trade[4].

Key Takeaways

  • Record High Production: Global cocaine hydrochloride production has reached all-time highs, driven by increased efficiency and production in Colombia.
  • Elastic Demand: The demand for cocaine is elastic and increases with income, making it a normal good.
  • Efficient Manufacturing: Improvements in manufacturing processes have increased production capacities.
  • Law Enforcement Efforts: Record-high seizures and dismantling of large-scale facilities indicate strong law enforcement actions.
  • Future Expansion: The market is likely to expand into new regions, particularly Africa and Asia.

FAQs

  1. What was the global production of cocaine hydrochloride in 2019?

    • In 2019, global cocaine hydrochloride production was estimated to be around 1,784 tonnes[1].
  2. How did the COVID-19 pandemic affect cocaine production?

    • The pandemic caused temporary disruptions, including a drop in coca leaf prices and fuel shortages, but production quickly recovered and continued to rise[1].
  3. What is the difference between powder cocaine and crack cocaine?

    • Powder cocaine (cocaine hydrochloride) is a white powder, while crack cocaine is the base form of cocaine, often associated with different demographics and usage patterns[2].
  4. What are the economic characteristics of the cocaine market?

    • The market operates under imperfect competition, exhibits internal economies of scale, and has elastic demand that increases with income[4].
  5. What are the law enforcement efforts against cocaine production?

    • Law enforcement has been actively dismantling large-scale manufacturing facilities and seizing record-high amounts of cocaine, indicating strong efforts to disrupt the supply chain[1][5].

Sources

  1. EU Drug Markets: Cocaine — In-depth analysis by the EMCDDA and Europol

  2. Crack Cocaine vs Cocaine - Sanctuary Lodge

  3. Legal Cocaine Market | Industry Analysis | Forecast 2025 - Technavio

  4. Demand and Supply in the Cocaine Market: An Empirical Study

  5. UNODC Global Report on Cocaine 2023

More… ↓

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