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Last Updated: December 22, 2024

Dinoprost tromethamine - Generic Drug Details


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What are the generic sources for dinoprost tromethamine and what is the scope of patent protection?

Dinoprost tromethamine is the generic ingredient in one branded drug marketed by Pharmacia And Upjohn and is included in one NDA. Additional information is available in the individual branded drug profile pages.

There is one drug master file entry for dinoprost tromethamine.

Summary for dinoprost tromethamine
Medical Subject Heading (MeSH) Categories for dinoprost tromethamine
Anatomical Therapeutic Chemical (ATC) Classes for dinoprost tromethamine

US Patents and Regulatory Information for dinoprost tromethamine

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Pharmacia And Upjohn PROSTIN F2 ALPHA dinoprost tromethamine INJECTABLE;INJECTION 017434-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for dinoprost tromethamine

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Pharmacia And Upjohn PROSTIN F2 ALPHA dinoprost tromethamine INJECTABLE;INJECTION 017434-001 Approved Prior to Jan 1, 1982 3,657,327 ⤷  Subscribe
Pharmacia And Upjohn PROSTIN F2 ALPHA dinoprost tromethamine INJECTABLE;INJECTION 017434-001 Approved Prior to Jan 1, 1982 3,778,506 ⤷  Subscribe
Pharmacia And Upjohn PROSTIN F2 ALPHA dinoprost tromethamine INJECTABLE;INJECTION 017434-001 Approved Prior to Jan 1, 1982 3,706,789 ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

Dinoprost tromethamine Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Dinoprost Tromethamine

Overview of Dinoprost Tromethamine

Dinoprost tromethamine, a synthetic analogue of prostaglandin F2α, is a crucial pharmaceutical compound used in both human and veterinary medicine. It is known for its role in inducing labor, aborting second-trimester pregnancies, and causing luteolysis in animals[2][5].

Market Size and Growth

The global market for dinoprost tromethamine is projected to experience significant growth over the next few years. As of 2023, the global market was valued at approximately $73.25 million, and it is expected to reach $102.72 million by 2030, growing at a Compound Annual Growth Rate (CAGR) of around 4.5%[4].

In the US and Canada, the market is also anticipated to grow, increasing from $22.90 million in 2023 to $31.07 million by 2030, with a CAGR of 4.24%[1].

Key Market Drivers

Increasing Demand in Veterinary Medicine

Dinoprost tromethamine is widely used in veterinary medicine to induce luteolysis in cows, sows, and mares. The growing livestock industry and the need for efficient reproductive management in animals are driving the demand for this drug[2].

Human Medical Applications

In human medicine, dinoprost tromethamine is used for aborting second-trimester pregnancies and in cases of incomplete abortion. The increasing need for safe and effective abortion methods, along with advancements in obstetric care, contributes to the market growth[5].

Regulatory Environment

Regulatory approvals and updates play a crucial role in the market dynamics. For instance, Health Canada's efforts to modernize regulations and expedite the approval process for new drugs, including those for veterinary use, can influence the market positively[3].

Financial Trajectory

Revenue Projections

The revenue from dinoprost tromethamine is expected to rise steadily over the forecast period. The global market revenue is projected to increase by nearly $30 million from 2023 to 2030, indicating a robust financial trajectory[4].

Regional Market Performance

  • US and Canada: The market in these regions is expected to grow from $22.90 million in 2023 to $31.07 million by 2030, driven by the increasing demand in both veterinary and human medical sectors[1].
  • Global Market: The global revenue is anticipated to rise from $73.25 million in 2023 to $102.72 million by 2030, reflecting a broader acceptance and increasing use of the drug worldwide[4].

Competitive Landscape

The market for dinoprost tromethamine is characterized by a few key players, primarily pharmaceutical companies that specialize in reproductive health and veterinary medicines. The competitive landscape is influenced by factors such as product quality, pricing, and regulatory approvals.

Challenges and Opportunities

Challenges

  • Toxicity and Side Effects: While dinoprost tromethamine is generally safe, it can cause side effects such as nausea, vomiting, and diarrhea. High doses can lead to more severe adverse effects, which may impact market growth[5].
  • Regulatory Hurdles: The approval process for pharmaceuticals is stringent, and any changes in regulatory requirements can affect the market dynamics[3].

Opportunities

  • Expanding Veterinary Use: The growing livestock industry presents a significant opportunity for the increased use of dinoprost tromethamine in veterinary medicine.
  • Advancements in Human Medicine: Continuous advancements in obstetric care and the need for safe abortion methods provide opportunities for the drug in human medicine[5].

Toxicological and Pharmacological Profile

Dinoprost tromethamine has a short half-life and is rapidly cleared from the body, which reduces the risk of accumulation and toxicity. It is of low acute oral and parenteral toxicity, and repeated doses have shown no significant toxic effects in various animal studies[2].

Conclusion

The market for dinoprost tromethamine is poised for growth, driven by increasing demand in both veterinary and human medical sectors. The financial trajectory indicates a steady rise in revenue, with regional markets contributing significantly to the global growth.

Key Takeaways

  • Global Market Growth: Expected to grow from $73.25 million in 2023 to $102.72 million by 2030.
  • US and Canada Market: Projected to increase from $22.90 million in 2023 to $31.07 million by 2030.
  • Key Drivers: Increasing demand in veterinary medicine and human medical applications.
  • Regulatory Influence: Modernization of regulations and expedited approval processes.
  • Challenges: Toxicity and side effects, regulatory hurdles.
  • Opportunities: Expanding veterinary use, advancements in human medicine.

FAQs

What is dinoprost tromethamine used for?

Dinoprost tromethamine is used to induce labor, abort second-trimester pregnancies, and cause luteolysis in animals such as cows, sows, and mares[2][5].

What is the expected growth rate of the global dinoprost tromethamine market?

The global market is expected to grow at a CAGR of around 4.5% from 2023 to 2030[4].

What are the key drivers of the dinoprost tromethamine market?

The key drivers include increasing demand in veterinary medicine and human medical applications, along with favorable regulatory environments[2][5].

What are the potential side effects of dinoprost tromethamine?

Common side effects include nausea, vomiting, and diarrhea. High doses can lead to more severe adverse effects such as bronchial constriction and uterine contractions[5].

Is dinoprost tromethamine approved for use in humans in the US?

Dinoprost tromethamine is not approved for use in humans in the US but is approved in other countries for specific medical applications[5].

Sources

  1. MarketResearch.com: Global Dinoprost Tromethamine Market Insights, Forecast to 2030.
  2. EMA: Dinoprost tromethamine summary report - Committee for Veterinary Medicinal Products.
  3. Health Canada: Drug and medical device highlights 2018.
  4. GIIR Research: Global Dinoprost Tromethamine Market Insights, Forecast to 2030.
  5. DrugBank: Dinoprost tromethamine: Uses, Interactions, Mechanism of Action.

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