Disulfiram - Generic Drug Details

What are the generic drug sources for disulfiram and what is the scope of patent protection?

Disulfiram is the generic ingredient in two branded drugs marketed by Odyssey Pharms, Teva Womens, Alvogen, Chartwell Molecules, Dash Pharms, Hikma, Sigmapharm Labs Llc, Strides Pharma, Watson Labs, and Watson Labs Teva, and is included in fourteen NDAs. Additional information is available in the individual branded drug profile pages.

There are seven drug master file entries for disulfiram. Four suppliers are listed for this compound.

Summary for disulfiram

US Patents:	0
Tradenames:	2
Applicants:	10
NDAs:	14
Drug Master File Entries:	7
Finished Product Suppliers / Packagers:	4
Raw Ingredient (Bulk) Api Vendors:	131
Clinical Trials:	67
Patent Applications:	6,356
Drug Prices:	Drug price trends for disulfiram
What excipients (inactive ingredients) are in disulfiram?	disulfiram excipients list
DailyMed Link:	disulfiram at DailyMed

See drug prices for disulfiram

Recent Clinical Trials for disulfiram

Identify potential brand extensions & 505(b)(2) entrants

Sponsor	Phase
College of Pharmaceutical Sciences at Zhejiang University	N/A
First People's Hospital of Hangzhou	N/A
The Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University	N/A

See all disulfiram clinical trials

Pharmacology for disulfiram

Drug Class	Aldehyde Dehydrogenase Inhibitor
Mechanism of Action	Acetyl Aldehyde Dehydrogenase Inhibitors

Medical Subject Heading (MeSH) Categories for disulfiram

Acetaldehyde Dehydrogenase Inhibitors

Alcohol Deterrents

Anatomical Therapeutic Chemical (ATC) Classes for disulfiram

N07BB	Drugs used in alcohol dependence
N07B	DRUGS USED IN ADDICTIVE DISORDERS
N07	OTHER NERVOUS SYSTEM DRUGS
N	Nervous system

P03AA	Sulfur containing products
P03A	ECTOPARASITICIDES, INCL. SCABICIDES
P03	ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
P	Antiparasitic products, insecticides and repellents

US Patents and Regulatory Information for disulfiram

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Strides Pharma	DISULFIRAM	disulfiram	TABLET;ORAL	088793-001	Aug 14, 1984		DISCN	No	No
Strides Pharma	DISULFIRAM	disulfiram	TABLET;ORAL	088792-001	Aug 14, 1984		DISCN	No	No
Teva Womens	ANTABUSE	disulfiram	TABLET;ORAL	007883-002	Approved Prior to Jan 1, 1982		DISCN	Yes	No
Sigmapharm Labs Llc	DISULFIRAM	disulfiram	TABLET;ORAL	091619-002	Mar 28, 2011	AB	RX	No	No
Watson Labs	DISULFIRAM	disulfiram	TABLET;ORAL	087974-001	Aug 5, 1983		DISCN	No	No

Disulfiram Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Disulfiram

Overview of Disulfiram Market

The disulfiram market is experiencing significant growth, driven by increasing cases of alcohol addiction and rising patient awareness about treatment options. Here’s a detailed look at the market dynamics and financial trajectory of disulfiram.

Current Market Size and Forecast

As of 2023, the disulfiram market was valued at USD 375.19 million. It is expected to reach USD 392.75 million in 2024 and is projected to grow at a Compound Annual Growth Rate (CAGR) of 4.81% to reach USD 521.63 million by 2030[2][3][4].

Market Segmentation

The disulfiram market is segmented based on several key factors:

By Type

• The market is categorized into different purity levels of disulfiram, such as 97%, 98%, and 99% purity[1].

By Application

• Disulfiram is used in various applications, including industrial, chemical industry, and other sectors. However, its primary use is in the treatment of alcoholism[1].

By Distribution Channel

• The drug is distributed through hospital pharmacies, online pharmacies, and retail pharmacies[3].

By Geographical Region

• The market is analyzed across regions such as North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. Each region has its unique dynamics influenced by local healthcare policies, economic conditions, and healthcare infrastructure[2][3][4].

Market Drivers

Several factors are driving the growth of the disulfiram market:

Growing Cases of Alcohol Addiction

• The increasing prevalence of alcohol dependency worldwide is a significant driver. As more people seek treatment for alcoholism, the demand for disulfiram is rising[2][3][4].

Increasing Patient Awareness and Treatment-Seeking Rate

• Higher awareness about alcohol dependency treatments and an increase in the number of patients seeking treatment are boosting the market[3][4].

Market Restraints

Despite the growth, there are some restraints affecting the market:

Side Effects Associated with Disulfiram

• Side effects such as liver toxicity and allergic reactions are significant concerns that can hamper market growth. These adverse effects necessitate careful monitoring and management[3][4].

Market Opportunities

There are several opportunities that could further propel the market:

Favorable Government Efforts

• Governments' efforts to curb alcohol use and support alcoholism treatment programs create a favorable environment for the adoption of disulfiram[3][4].

Innovations in Drug Delivery Systems

• Research and development aimed at creating more patient-friendly formulations with fewer side effects are expected to enhance market growth[3].

Market Challenges

The market also faces several challenges:

Effectiveness Issues

• Questions about the effectiveness of disulfiram, particularly when used alone without counseling and psychological support, can impact its adoption[3][4].

Regional Insights

The disulfiram market varies significantly across different regions:

Americas

• In the Americas, the market is expanding rapidly due to established healthcare infrastructure and awareness about alcohol dependency treatments. Insurance coverage and treatment programs that include disulfiram support its availability[2][3][4].

Europe

• Europe, particularly Northern and Western European countries, has higher awareness and treatment rates for alcoholism. The regulatory environment and healthcare networks in Europe significantly support the accessibility of disulfiram[2][3][4].

Asia-Pacific

• The Asia-Pacific region shows a varied landscape, with countries like Australia and Japan having better access to disulfiram due to supportive healthcare systems and regulations[2][3][4].

Middle East and Africa

• Cultural attitudes towards alcohol and alcoholism treatment are expanding the adoption of disulfiram in these regions, although access can be variable due to local healthcare policies and economic conditions[2][3][4].

Competitive Landscape

The disulfiram market is competitive, with several key players:

Key Company Profiles

• Companies such as Abbott Laboratories, Alkem Laboratories Ltd., Allergan plc, Aspen Pharmacare Holdings Limited, Aurobindo Pharma Limited, and others are significant players in the market. These companies are innovating and expanding their market presence through various strategies[2][4].

Market Share Analysis

• The market share analysis provides insights into the performance of these vendors, including their revenue, customer base, and other vital metrics. This helps in understanding the competitive nature of the sector and devising effective strategies to gain a competitive edge[2].

Financial Trajectory

The financial trajectory of the disulfiram market is positive, with steady growth projected over the next few years:

Revenue Growth

• The market is expected to grow from USD 375.19 million in 2023 to USD 521.63 million by 2030, at a CAGR of 4.81%[2][3][4].

Investment and Development

• Companies are investing in research and development to improve drug formulations and reduce side effects, which is expected to drive further growth[3].

Regulatory Support

• Favorable regulatory environments, especially in regions like Europe and North America, support the financial growth of the market by ensuring accessibility and reimbursement for disulfiram treatments[2][3][4].

Strategy Analysis and Recommendations

For organizations seeking to establish a strong presence in the global disulfiram market, several strategies are recommended:

Thorough Market Analysis

• Conducting a thorough analysis of market dynamics, including supply and demand levels, helps in designing strategies and making informed investment decisions[2].

Focus on Innovation

• Investing in research and development to create more patient-friendly formulations can help companies capitalize on future opportunities and mitigate the impact of side effects[3].

Regional Focus

• Understanding regional differences and tailoring strategies accordingly can help companies leverage local healthcare policies, economic conditions, and cultural attitudes to their advantage[2][3][4].

Key Takeaways

• The disulfiram market is growing steadily, driven by increasing cases of alcohol addiction and rising patient awareness.
• The market is segmented by type, application, distribution channel, and geographical region.
• Key drivers include growing alcohol addiction cases and increasing patient awareness, while side effects and effectiveness issues are significant restraints.
• Regional dynamics vary, with established healthcare infrastructure in the Americas and Europe supporting market growth.
• The competitive landscape is dominated by several major pharmaceutical companies.
• The financial trajectory is positive, with projected growth to USD 521.63 million by 2030.

FAQs

What is the current market size of the disulfiram market?

The disulfiram market was valued at USD 375.19 million in 2023[2][3][4].

What is the projected growth rate of the disulfiram market?

The market is expected to grow at a CAGR of 4.81% from 2023 to 2030[2][3][4].

What are the main drivers of the disulfiram market?

The main drivers include growing cases of alcohol addiction and increasing patient awareness and treatment-seeking rates[2][3][4].

What are the significant restraints affecting the disulfiram market?

Significant restraints include side effects associated with disulfiram and issues related to its effectiveness[3][4].

Which regions are expected to see significant growth in the disulfiram market?

The Americas, Europe, and certain countries in the Asia-Pacific region are expected to see significant growth due to established healthcare infrastructure and supportive regulatory environments[2][3][4].

Sources

1. Market Research Intellect: Global Disulfiram Market Size, Scope And Forecast Report.
2. GII Research: Disulfiram Market by Indication, Distribution Channel.
3. GlobeNewswire: Disulfiram Presents a $521+ Million Industry Opportunity by 2030.
4. 360iResearch: Disulfiram Market Size & Share 2025-2030.