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Last Updated: December 22, 2024

Hydrocortisone; neomycin sulfate - Generic Drug Details


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Summary for hydrocortisone; neomycin sulfate
US Patents:0
Tradenames:10
Applicants:10
NDAs:19
Clinical Trials: 1
DailyMed Link:hydrocortisone; neomycin sulfate at DailyMed
Recent Clinical Trials for hydrocortisone; neomycin sulfate

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SponsorPhase
Huro Biotech Joint Stock CompanyN/A
Vietstar Biomedical ResearchN/A

See all hydrocortisone; neomycin sulfate clinical trials

Anatomical Therapeutic Chemical (ATC) Classes for hydrocortisone; neomycin sulfate
A01AB Antiinfectives and antiseptics for local oral treatment
A01A STOMATOLOGICAL PREPARATIONS
A01 STOMATOLOGICAL PREPARATIONS
A Alimentary tract and metabolism
A01AC Corticosteroids for local oral treatment
A01A STOMATOLOGICAL PREPARATIONS
A01 STOMATOLOGICAL PREPARATIONS
A Alimentary tract and metabolism
A07AA Antibiotics
A07A INTESTINAL ANTIINFECTIVES
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A Alimentary tract and metabolism
A07EA Corticosteroids acting locally
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A Alimentary tract and metabolism
B05CA Antiinfectives
B05C IRRIGATING SOLUTIONS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B Blood and blood forming organs
C05AA Corticosteroids
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05 VASOPROTECTIVES
C Cardiovascular system
D06AX Other antibiotics for topical use
D06A ANTIBIOTICS FOR TOPICAL USE
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D Dermatologicals
D07AA Corticosteroids, weak (group I)
D07A CORTICOSTEROIDS, PLAIN
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
D07XA Corticosteroids, weak, other combinations
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
H02AB Glucocorticoids
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H Systemic hormonal preparations, excluding sex hormones and insulins
H02AB Glucocorticoids
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H Systemic hormonal preparations, excluding sex hormones and insulins
J01GB Other aminoglycosides
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J Antiinfectives for systemic use
R02AB Antibiotics
R02A THROAT PREPARATIONS
R02 THROAT PREPARATIONS
R Respiratory system
S01AA Antibiotics
S01A ANTIINFECTIVES
S01 OPHTHALMOLOGICALS
S Sensory organs
S01BA Corticosteroids, plain
S01B ANTIINFLAMMATORY AGENTS
S01 OPHTHALMOLOGICALS
S Sensory organs
S01BA Corticosteroids, plain
S01B ANTIINFLAMMATORY AGENTS
S01 OPHTHALMOLOGICALS
S Sensory organs
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01 OPHTHALMOLOGICALS
S Sensory organs
S02AA Antiinfectives
S02A ANTIINFECTIVES
S02 OTOLOGICALS
S Sensory organs
S02BA Corticosteroids
S02B CORTICOSTEROIDS
S02 OTOLOGICALS
S Sensory organs
S03AA Antiinfectives
S03A ANTIINFECTIVES
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S Sensory organs

US Patents and Regulatory Information for hydrocortisone; neomycin sulfate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Pharmafair NEOMYCIN SULFATE, POLYMYXIN B SULFATE & HYDROCORTISONE hydrocortisone; neomycin sulfate; polymyxin b sulfate SUSPENSION/DROPS;OTIC 062617-001 Sep 18, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sandoz NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE hydrocortisone; neomycin sulfate; polymyxin b sulfate SUSPENSION/DROPS;OTIC 062488-001 Nov 6, 1985 AT RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Amring Pharms NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE hydrocortisone; neomycin sulfate; polymyxin b sulfate SOLUTION/DROPS;OTIC 065216-001 Oct 31, 2005 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Amring Pharms NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE hydrocortisone; neomycin sulfate; polymyxin b sulfate SUSPENSION/DROPS;OTIC 065219-001 May 1, 2006 AT RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Hydrocortisone; neomycin sulfate Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Hydrocortisone and Neomycin Sulfate

Introduction

Hydrocortisone and neomycin sulfate are two widely used pharmaceuticals, each with distinct applications and market dynamics. This article delves into the market trends, financial performance, and key drivers influencing these drugs.

Hydrocortisone Market Overview

Market Size and Growth

The global hydrocortisone market is experiencing robust growth. As of 2023, the market size was estimated at $1.43 billion and is projected to reach $1.96 billion by 2028, growing at a compound annual growth rate (CAGR) of 6.6%[2].

Key Drivers

The growth in the hydrocortisone market is driven by several factors:

  • Rising Prevalence of Skin Disorders: Increased cases of dermatitis, eczema, and other skin conditions are driving the demand for hydrocortisone.
  • Technological Advancements: Improvements in formulation and delivery methods are enhancing the efficacy and user experience of hydrocortisone products.
  • Increased Investment in R&D: Continuous research and development are leading to new applications and improved formulations.
  • Growing Disposable Income: As global disposable income increases, more people can afford healthcare products, including hydrocortisone[2].

Regional Market Performance

North America holds a significant share of the global hydrocortisone market, with a market size of $540.88 million in 2024 and a CAGR of 4.7% from 2024 to 2031. Europe and Asia Pacific also have substantial market shares, with CAGRs of 5.0% and 8.5%, respectively[2].

Neomycin Sulfate Market Overview

Applications and Uses

Neomycin sulfate is an aminoglycoside antibiotic used in various formulations:

  • Oral Solution: Used as an adjunctive therapy in hepatic coma to reduce ammonia-forming bacteria in the intestinal tract.
  • Otic Suspensions: Combined with polymyxin B sulfates and hydrocortisone to treat bacterial infections in the external auditory canal.
  • Ophthalmic Preparations: Combined with polymyxin B sulfates and dexamethasone to treat inflammatory conditions and infections in the eye.
  • Topical Products: Used to prevent minor skin infections[1].

Market Dynamics

The market for neomycin sulfate is influenced by its specific applications and the demand for antibiotic and antifungal treatments. The combination products, such as those with hydrocortisone and polymyxin B sulfates, are particularly significant in the otic and ophthalmic markets.

Financial Performance

Revenue Growth for Hydrocortisone

Companies involved in the hydrocortisone market are experiencing significant revenue growth. For example, Eton Pharmaceuticals reported a 109% year-over-year increase in product sales and royalty revenue in Q4 2023, reaching $7.3 million[2].

Cost Benefits of Hydrocortisone Therapy

Adjunctive hydrocortisone therapy has shown significant cost benefits, particularly in critical care settings. A study estimated that this therapy could result in a monetized benefit of up to $25,539 per patient by reducing ICU stays, vasopressor-free days, and ventilation-free days[2].

Combination Therapies: Hydrocortisone and Neomycin Sulfate

CORTISPORIN Otic Solution

The combination of hydrocortisone, neomycin sulfate, and polymyxin B sulfate in CORTISPORIN otic solution is a notable example. This formulation is used to treat superficial bacterial infections of the external auditory canal and has been determined by the FDA not to have been withdrawn from sale for reasons of safety or effectiveness[3].

Market Trends and Future Outlook

Focus on Natural Ingredients and Combination Therapies

The hydrocortisone market is trending towards natural ingredients and combination therapies. Products that combine hydrocortisone with other active ingredients, such as neomycin sulfate, are gaining popularity due to their enhanced efficacy and broader therapeutic applications[2].

Personalized Treatments and Sustainability

There is an increasing focus on personalized treatments and sustainability in the pharmaceutical industry. Hydrocortisone and neomycin sulfate products that align with these trends are likely to see increased demand in the future[2].

Regional Analysis

North America, Europe, and Asia Pacific

These regions are significant contributors to the global markets for both hydrocortisone and neomycin sulfate. North America holds a major share, followed by Europe and Asia Pacific, which are also experiencing robust growth due to increasing healthcare spending and improving access to healthcare products[2][4].

Key Takeaways

  • Hydrocortisone Market Growth: The hydrocortisone market is growing at a CAGR of 6.6% from 2023 to 2028.
  • Neomycin Sulfate Applications: Neomycin sulfate is used in various formulations, including oral, otic, ophthalmic, and topical products.
  • Combination Therapies: Combination products like CORTISPORIN otic solution are significant in the market.
  • Cost Benefits: Adjunctive hydrocortisone therapy shows significant cost benefits in critical care settings.
  • Regional Performance: North America, Europe, and Asia Pacific are key regions driving the growth of these markets.

FAQs

What is the projected market size of the hydrocortisone market by 2028?

The hydrocortisone market is expected to reach $1.96 billion by 2028, growing at a CAGR of 6.6% from 2023 to 2028[2].

What are the main drivers of the hydrocortisone market growth?

The main drivers include the rising prevalence of skin disorders, technological advancements, increased investment in R&D, growing disposable income, and expanded distribution channels[2].

What are the primary uses of neomycin sulfate?

Neomycin sulfate is used as an adjunctive therapy in hepatic coma, in otic suspensions for external auditory canal infections, in ophthalmic preparations for eye infections, and in topical products to prevent minor skin infections[1].

What is the significance of CORTISPORIN otic solution in the market?

CORTISPORIN otic solution, a combination of hydrocortisone, neomycin sulfate, and polymyxin B sulfate, is used to treat superficial bacterial infections of the external auditory canal and has been determined by the FDA not to have been withdrawn from sale for reasons of safety or effectiveness[3].

What are the cost benefits of adjunctive hydrocortisone therapy?

Adjunctive hydrocortisone therapy can result in a monetized benefit of up to $25,539 per patient by reducing ICU stays, vasopressor-free days, and ventilation-free days[2].

Cited Sources

  1. DrugBank Online: Neomycin: Uses, Interactions, Mechanism of Action.
  2. DrugPatentWatch: Generic HYDROCORTISONE INN entry, drug patent expiration.
  3. Federal Register: Notice - CORTISPORIN (hydrocortisone/neomycin sulfate/polymyxin B sulfate) otic solution.
  4. Transparency Market Research: Hydrocortisone Market | Global Industry Report, 2028.

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