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Last Updated: December 22, 2024

Neomycin sulfate; triamcinolone acetonide - Generic Drug Details


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What are the generic sources for neomycin sulfate; triamcinolone acetonide and what is the scope of freedom to operate?

Neomycin sulfate; triamcinolone acetonide is the generic ingredient in two branded drugs marketed by Savage Labs, Fougera, and Pharmaderm, and is included in six NDAs. Additional information is available in the individual branded drug profile pages.

Summary for neomycin sulfate; triamcinolone acetonide
US Patents:0
Tradenames:2
Applicants:3
NDAs:6
DailyMed Link:neomycin sulfate; triamcinolone acetonide at DailyMed
Anatomical Therapeutic Chemical (ATC) Classes for neomycin sulfate; triamcinolone acetonide
A01AB Antiinfectives and antiseptics for local oral treatment
A01A STOMATOLOGICAL PREPARATIONS
A01 STOMATOLOGICAL PREPARATIONS
A Alimentary tract and metabolism
A01AC Corticosteroids for local oral treatment
A01A STOMATOLOGICAL PREPARATIONS
A01 STOMATOLOGICAL PREPARATIONS
A Alimentary tract and metabolism
A07AA Antibiotics
A07A INTESTINAL ANTIINFECTIVES
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A Alimentary tract and metabolism
B05CA Antiinfectives
B05C IRRIGATING SOLUTIONS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B Blood and blood forming organs
C05AA Corticosteroids
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05 VASOPROTECTIVES
C Cardiovascular system
D06AX Other antibiotics for topical use
D06A ANTIBIOTICS FOR TOPICAL USE
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D Dermatologicals
D07AB Corticosteroids, moderately potent (group II)
D07A CORTICOSTEROIDS, PLAIN
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
D07XB Corticosteroids, moderately potent, other combinations
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D Dermatologicals
H02AB Glucocorticoids
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H Systemic hormonal preparations, excluding sex hormones and insulins
J01GB Other aminoglycosides
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J Antiinfectives for systemic use
R01AD Corticosteroids
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01 NASAL PREPARATIONS
R Respiratory system
R02AB Antibiotics
R02A THROAT PREPARATIONS
R02 THROAT PREPARATIONS
R Respiratory system
R03BA Glucocorticoids
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R Respiratory system
S01AA Antibiotics
S01A ANTIINFECTIVES
S01 OPHTHALMOLOGICALS
S Sensory organs
S01BA Corticosteroids, plain
S01B ANTIINFLAMMATORY AGENTS
S01 OPHTHALMOLOGICALS
S Sensory organs
S02AA Antiinfectives
S02A ANTIINFECTIVES
S02 OTOLOGICALS
S Sensory organs
S03AA Antiinfectives
S03A ANTIINFECTIVES
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S Sensory organs

US Patents and Regulatory Information for neomycin sulfate; triamcinolone acetonide

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Savage Labs MYTREX A neomycin sulfate; triamcinolone acetonide OINTMENT;TOPICAL 062609-001 May 23, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fougera NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE neomycin sulfate; triamcinolone acetonide OINTMENT;TOPICAL 062608-001 May 23, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Savage Labs MYTREX A neomycin sulfate; triamcinolone acetonide CREAM;TOPICAL 062598-001 Jul 21, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pharmaderm NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE neomycin sulfate; triamcinolone acetonide CREAM;TOPICAL 062595-001 Jul 21, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pharmaderm NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE neomycin sulfate; triamcinolone acetonide OINTMENT;TOPICAL 062607-001 May 23, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fougera NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE neomycin sulfate; triamcinolone acetonide CREAM;TOPICAL 062600-001 Jul 21, 1986 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Neomycin sulfate; triamcinolone acetonide Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Neomycin Sulfate and Triamcinolone Acetonide

Introduction to Neomycin Sulfate and Triamcinolone Acetonide

Neomycin sulfate and triamcinolone acetonide are two distinct pharmaceuticals with different therapeutic applications. Neomycin sulfate is an aminoglycoside antibiotic, while triamcinolone acetonide is a synthetic corticosteroid. This article will delve into the market dynamics and financial trajectories of these drugs.

Neomycin Sulfate Market Overview

Market Size and Growth

The global neomycin sulfate market was valued at approximately 13 thousand tonnes in 2023 and is projected to grow at a Compound Annual Growth Rate (CAGR) of 3.5% until 2034[4].

Leading Consumers

North America is the leading consumer of neomycin sulfate globally, driven by its widespread use in various medical and veterinary applications[4].

Applications

Neomycin sulfate is used in several formulations, including oral solutions for hepatic coma, otic suspensions for external auditory canal infections, and ophthalmic solutions for treating inflammatory and infectious ocular conditions. It is often combined with other antibiotics like polymyxin B sulfates and corticosteroids like dexamethasone[3].

Market Drivers

The growth of the neomycin sulfate market is driven by its effectiveness in treating bacterial infections and its inclusion in various pharmaceutical preparations. The increasing demand for antibiotics in both human and veterinary medicine also contributes to its market expansion[4].

Triamcinolone Acetonide Market Overview

Market Size and Growth

The triamcinolone market was valued at USD 874.2 million in 2023 and is anticipated to grow at a CAGR of 3.4% from 2024 to 2032, reaching a projected value of USD 1.2 billion by 2032[1].

Segmentation

The triamcinolone market is segmented by type (cream, injections, inhalers, and others), application (eczema, dermatitis, allergies, psoriasis, and others), and end-user (drug stores, hospitals, and others). The cream segment holds the majority of the market share, and the eczema segment dominates in terms of application[1].

Regional Performance

North America, particularly the U.S., accounts for a significant share of the global triamcinolone market, with the U.S. market valued at USD 305.9 million in 2023. Other regions, such as Germany and India, are also expected to show significant growth during the forecast period[1].

Market Drivers

The growth of the triamcinolone market is driven by the increasing prevalence of skin conditions, growing awareness of timely treatment, and the availability of efficient active ingredients. Regulatory approvals for new and advanced triamcinolone formulations also contribute to market growth[1].

Financial Trajectory

Revenue Projections

For neomycin sulfate, the market is expected to grow steadily, driven by its use in various medical applications. The volume is projected to increase from 13 thousand tonnes in 2023 to a higher figure by 2034, reflecting a CAGR of 3.5%[4].

For triamcinolone acetonide, the market is anticipated to reach USD 1.2 billion by 2032, growing at a CAGR of 3.4% from 2024 to 2032. This growth is supported by the increasing demand for dermatological treatments and the expansion of end-user segments such as drug stores and hospitals[1].

Cost and Pricing

The cost and pricing of these drugs can vary based on the formulation, application, and region. For instance, triamcinolone acetonide formulations like creams and injections have different price points, with creams being more widely used and potentially more affordable. Neomycin sulfate, especially in combination products, may have varying prices depending on the specific formulation and brand[1][3].

Competitive Landscape

Neomycin Sulfate

The neomycin sulfate market is characterized by the presence of several manufacturers, both large and small. The market is relatively stable, with established players maintaining a significant share due to their experience and expertise in antibiotic production and distribution[4].

Triamcinolone Acetonide

The triamcinolone market is highly fragmented, with numerous generic manufacturers offering various formulations. Established vendors often outsource manufacturing to contract manufacturers in developing countries to reduce costs. This fragmentation allows for a competitive pricing environment and a wide range of product availability[1].

Regulatory Environment

Neomycin Sulfate

Neomycin sulfate is regulated under various pharmaceutical guidelines, ensuring its safe use in medical and veterinary applications. For example, it is indicated for use in infections caused by susceptible bacteria to prevent the development of drug-resistant bacteria[3].

Triamcinolone Acetonide

Triamcinolone acetonide is subject to regulatory approvals for new and advanced formulations, which positively impacts its market growth. Regulatory bodies ensure that these formulations meet safety and efficacy standards before they are made available in the market[1].

Challenges and Opportunities

Challenges

Both markets face challenges such as the potential for side effects and the risk of developing drug-resistant bacteria. For triamcinolone acetonide, long-term use can lead to side effects like polyuria, hyperphagia, and muscle weakness, as seen in animal studies[2].

Opportunities

The increasing prevalence of skin conditions and bacterial infections presents significant opportunities for growth. Advances in formulation technology and the expansion into new regions, such as emerging markets in Asia, can further drive market expansion for both neomycin sulfate and triamcinolone acetonide[1][4].

Key Applications and Therapeutic Uses

Neomycin Sulfate

Neomycin sulfate is used in various therapeutic applications, including:

  • Oral Solutions: For adjunctive therapy in hepatic coma.
  • Otic Suspensions: For treating superficial bacterial infections of the external auditory canal.
  • Ophthalmic Solutions: For treating steroid-responsive inflammatory ocular conditions[3].

Triamcinolone Acetonide

Triamcinolone acetonide is primarily used for its anti-inflammatory properties, treating conditions such as:

  • Eczema: Dominates the application segment with a significant revenue share.
  • Dermatitis: Another major application area.
  • Allergies and Psoriasis: Also treated with triamcinolone acetonide formulations[1].

Case Studies and Clinical Evidence

Neomycin Sulfate

Clinical studies have shown the efficacy of neomycin sulfate in treating bacterial infections. For example, its use in combination with polymyxin B sulfates and dexamethasone has been effective in treating ocular infections and inflammatory conditions[3].

Triamcinolone Acetonide

Studies have demonstrated the effectiveness of triamcinolone acetonide in treating various inflammatory conditions. For instance, intravitreal triamcinolone acetonide injections have shown benefits in treating retinal vein occlusions, and its use in Dupuytren disease has shown significant reduction in nodule sizes over a 5-year follow-up period[2].

Conclusion

The markets for neomycin sulfate and triamcinolone acetonide are driven by distinct factors but share common growth trajectories. Neomycin sulfate, as an antibiotic, is crucial in treating bacterial infections, while triamcinolone acetonide, as a corticosteroid, is vital in managing inflammatory and skin conditions. Both markets are expected to grow steadily, driven by increasing demand and advancements in formulation technology.

Key Takeaways

  • Neomycin Sulfate: Expected to grow at a CAGR of 3.5% until 2034, driven by its use in treating bacterial infections.
  • Triamcinolone Acetonide: Anticipated to grow at a CAGR of 3.4% from 2024 to 2032, driven by the increasing prevalence of skin conditions and regulatory approvals for new formulations.
  • Market Segmentation: Both markets are segmented based on type, application, and end-user, with North America being a significant region for both.
  • Regulatory Environment: Both drugs are subject to strict regulatory guidelines to ensure safety and efficacy.

FAQs

Q: What is the current market size of neomycin sulfate in terms of volume?

A: The global market size of neomycin sulfate was approximately 13 thousand tonnes in 2023[4].

Q: Which region dominates the triamcinolone acetonide market?

A: North America, particularly the U.S., accounts for a significant share of the global triamcinolone market[1].

Q: What are the primary applications of triamcinolone acetonide?

A: The primary applications include treating eczema, dermatitis, allergies, and psoriasis[1].

Q: What are the potential side effects of long-term triamcinolone acetonide use?

A: Long-term use can lead to side effects such as polyuria, hyperphagia, and muscle weakness[2].

Q: How does the regulatory environment impact the market for these drugs?

A: Regulatory approvals and guidelines ensure the safe and effective use of these drugs, positively impacting market growth and ensuring compliance with safety standards[1][3].

Sources

  1. GMI Insights: Triamcinolone Market 2024 – 2032 Industry Growth Report.
  2. Science.gov: Topics by Science.gov - Triamcinolone acetonide.
  3. DrugBank Online: Neomycin: Uses, Interactions, Mechanism of Action.
  4. ChemAnalyst: Neomycin Sulphate Market Size, Share, Growth & Forecast.

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