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Last Updated: December 22, 2024

Trimeprazine tartrate - Generic Drug Details


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What are the generic sources for trimeprazine tartrate and what is the scope of patent protection?

Trimeprazine tartrate is the generic ingredient in two branded drugs marketed by Allergan Herbert, Alpharma Us Pharms, and Morton Grove, and is included in three NDAs. Additional information is available in the individual branded drug profile pages.

There are four drug master file entries for trimeprazine tartrate.

Summary for trimeprazine tartrate
Medical Subject Heading (MeSH) Categories for trimeprazine tartrate

US Patents and Regulatory Information for trimeprazine tartrate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Morton Grove TRIMEPRAZINE TARTRATE trimeprazine tartrate SYRUP;ORAL 088285-001 Apr 11, 1985 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Allergan Herbert TEMARIL trimeprazine tartrate TABLET;ORAL 011316-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Allergan Herbert TEMARIL trimeprazine tartrate CAPSULE, EXTENDED RELEASE;ORAL 011316-004 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Trimeprazine tartrate Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Trimeprazine Tartrate

Introduction

Trimeprazine tartrate, a phenothiazine derivative, is widely used as an antihistamine, sedative, and antiemetic. Understanding its market dynamics and financial trajectory is crucial for pharmaceutical companies, investors, and healthcare professionals.

Market Overview

Trimeprazine tartrate is used in various medical applications, including the treatment of allergic reactions, pruritus, and as a sedative and antiemetic agent. Here are some key aspects of its market:

Therapeutic Uses

  • Antihistamine and Antipruritic: Trimeprazine tartrate is effective in blocking histamine receptors, particularly H1 receptors, which helps in alleviating symptoms of allergic reactions and itching[1][3][4].
  • Sedative and Hypnotic: It possesses sedative properties, making it useful for managing sleep disturbances, although more research is needed to confirm its efficacy in this area[1][4].
  • Antiemetic: It is active in suppressing vomiting, which is beneficial in various clinical settings[4].

Geographical Presence

Trimeprazine tartrate is used in human medicine in some countries, but it is more commonly utilized as a veterinary medication. In Russia, it is marketed under the brand name Teraligen for treating neurosis, depression, and anxiety[3].

Market Demand

The demand for trimeprazine tartrate can be analyzed from several perspectives:

Allergic Conditions

The prevalence of allergic conditions such as allergic rhinitis and urticaria drives the demand for antihistamines like trimeprazine tartrate. With increasing rates of allergies globally, the market for antihistamines is expected to grow[1].

Veterinary Use

Its widespread use in veterinary medicine, particularly for treating itching and allergic reactions in animals, contributes significantly to its market demand[1].

Sleep Disturbances

Although the evidence is inconclusive, the potential use of trimeprazine tartrate for improving sleep could open up new market opportunities if further research supports its efficacy[1].

Competitive Landscape

The market for trimeprazine tartrate is part of the broader antihistamine and sedative market. Here are some key competitive aspects:

Generic vs. Branded

Trimeprazine tartrate is available as a generic medication, which can affect its pricing and market share. Generic versions often compete with branded products, influencing the financial trajectory of the drug[3].

Alternative Treatments

The presence of other antihistamines and sedatives in the market can impact the demand for trimeprazine tartrate. Competitors include both older and newer generations of antihistamines, each with their own set of advantages and side effects[1].

Financial Trajectory

The financial performance of trimeprazine tartrate can be influenced by several factors:

Sales and Revenue

The revenue generated from trimeprazine tartrate sales is significant, particularly in regions where it is widely used in both human and veterinary medicine. However, the revenue can fluctuate based on market competition, regulatory changes, and the introduction of new treatments[3].

Cost and Pricing

The cost of production and pricing strategies play a crucial role in the financial trajectory. Generic versions of the drug tend to be cheaper, which can affect the pricing power of branded versions. Additionally, the cost of raw materials and manufacturing processes can impact the overall profitability[3].

Regulatory Environment

Regulatory approvals and compliance can significantly influence the financial performance of trimeprazine tartrate. For instance, changes in drug efficacy studies or safety regulations can impact its market presence and revenue[2][4].

Side Effects and Safety Concerns

The financial trajectory can also be affected by the drug's safety profile:

Common Side Effects

Side effects such as drowsiness, dry mouth, and dizziness are common but generally manageable. However, more serious side effects like seizures or abnormal movement disorders can impact patient compliance and overall market demand[1][4].

Rare but Serious Adverse Events

Rare but serious adverse events such as cardiac arrhythmias, neuroleptic malignant syndrome, and agranulocytosis can lead to legal and regulatory issues, affecting the drug's financial performance[4].

Future Outlook

The future outlook for trimeprazine tartrate is multifaceted:

Research and Development

Further research into its potential antimicrobial properties and its use in managing sleep disturbances could expand its market applications and improve its financial trajectory[1].

Market Expansion

Entering new markets, especially in regions with high prevalence of allergic conditions, can increase sales and revenue. However, this would require regulatory approvals and compliance with local healthcare standards[3].

Generic Competition

The presence of generic versions will continue to influence pricing and market share. Pharmaceutical companies may need to focus on differentiating their products through branding, marketing, and additional therapeutic benefits[3].

Key Takeaways

  • Trimeprazine tartrate is a versatile medication with applications in treating allergic reactions, pruritus, and as a sedative and antiemetic.
  • Its market demand is driven by the prevalence of allergic conditions and its use in veterinary medicine.
  • The competitive landscape includes both generic and branded antihistamines and sedatives.
  • Regulatory environment, safety profile, and ongoing research are critical factors influencing its financial trajectory.
  • Future growth opportunities include expanding into new markets and exploring additional therapeutic uses.

FAQs

Q: What are the primary therapeutic uses of trimeprazine tartrate? A: Trimeprazine tartrate is primarily used as an antihistamine, antipruritic, sedative, and antiemetic.

Q: Is trimeprazine tartrate approved for use in humans in the United States? A: No, trimeprazine tartrate is not approved for use in humans in the United States, although it is used in some other countries and commonly in veterinary medicine[3].

Q: What are the common side effects of trimeprazine tartrate? A: Common side effects include drowsiness, dry mouth, and dizziness. More serious side effects can include seizures or abnormal movement disorders[1][4].

Q: Does trimeprazine tartrate have antimicrobial properties? A: Research suggests that trimeprazine tartrate might possess antimicrobial properties, but further investigation is needed to confirm its efficacy as an antimicrobial agent[1].

Q: Can trimeprazine tartrate be used to treat sleep disturbances? A: While there is some evidence suggesting it may improve sleep, the results are inconclusive, and more research is required to determine its effectiveness in managing sleep problems[1].

Sources

  1. Smolecule: Trimeprazine tartrate.
  2. GovInfo: Highlights of This Issue.
  3. Inxight Drugs: TRIMEPRAZINE TARTRATE.
  4. Health Canada: PRODUCT MONOGRAPH PANECTYL (Trimeprazine Tartrate).

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