Claims for Patent: 3,935,267

Summary for Patent: 3,935,267

Title:	Tetrahydronaphthyloxy-aminopropanols and salts thereof
Abstract:	This invention relates to new tetrahydronaphthyloxy-aminopropanols and related compounds of the formula ##SPC1## And to salts of such compounds, which are useful in coronary diseases.
Inventor(s):	Hauck; Frederic Peter (Somerville, NJ), Cimarusti; Christopher M. (Somerset, NJ), Narayanan; Venkatachala Lakshmi (Hightstown, NJ)
Assignee:	E. R. Squibb & Sons, Inc. (Princeton, NJ)
Application Number:	05/203,865
Patent Claims:	1. Compounds of the structure ##SPC39## and stereoisomers and salts thereof, wherein R.sup.1 is lower alkyl; R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are the same or different and are selected from the group consisting of hydrogen and lower alkyl; and R.sup.8, R.sup.9 and R.sup.10 are the same or different and are selected from the group consisting of hydrogen, lower alkyl, lower alkoxy and cycloalkyl. 2. Compounds of the structure ##SPC40## and stereoisomers and salts thereof, wherein R.sup.1 is lower alkyl, and wherein the two adjacent hydroxy groups are in the cis configuration. 3. The compound in accordance with claim 2 having the name 2,3-cis-1,2,3,4-tetrahydro-5-[2-hydroxy-3-(isopropylamino)propoxy]-2,3-nap hthalenediol. 4. Compounds of the structure ##SPC41## stereoisomers thereof and salts thereof. 5. The compound in accordance with claim 4 having the name 2,3-cis-1,2,3,4-tetrahydro-5-[2-hydroxy-3-(tert-butylamino)propoxy]-2,3-na phthalenediol. 6. Compounds of the structure ##SPC42## and stereoisomers and salts thereof, wherein R.sup.1 is lower alkyl. 7. Compounds of the structure ##SPC43## and stereoisomers and salts thereof, wherein R.sup.1 is lower alkyl.