Claims for Patent: 4,837,208

Summary for Patent: 4,837,208

Title:	Treatment of human viral infections
Abstract:	Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
Inventor(s):	Rideout; Janet L. (Raleigh, NC), Barry; David W. (Chapel Hill, NC), Lehrman; Sandra N. (Durham, NC), St. Clair; Martha H. (Durham, NC), Furman; Phillip A. (Durham, NC)
Assignee:	Burroughs Wellcome Co. (Research Triangle Park, NC)
Application Number:	07/110,377
Patent Claims:	1. A method of treating a human having antibodies to the HTLV III virus which comprises administering to said human an effective HTLV III treatment amount of 3'-azido-3'-deoxythymidine. 2. A method of treating a human being having antibodies to the HTLV III virus which comprises administering to said human an effective HTLV III treatment amount of a pharmaceutically acceptable alkali metal, alkaline earth or ammonium salt of 3'-azido-3'-deoxythymidine. 3. A method of treating a human having antibodies to the HTLV III virus which comprises administering to said human an effective HTLV III treatment amount of a pharmaceutically acceptable salt of 3'-azido-3'-deoxythymidine.