Claims for Patent: 4,983,595
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Summary for Patent: 4,983,595
| Title: | Aqueous steroid formulations for nasal administration |
| Abstract: | A non-stinging aqueous anti-inflammatory steroid formulation suitable for intranasal administration comprises: an anti-inflammatory steroid in an amount between about 0.01% and about 0.05% (w/v); propylene glycol in an amount between about 2% and about 10% (w/v); PEG 400 in an amount between about 10% and about 25% (w/v); polysorbate 20 in an amount between about 1% and about 4% (w/v); an effective amount of a preservative; an effective amount of a stabilizer; an effective amount of an antioxidant; water; and pH buffering agent sufficient to adjust the pH of the resulting solution to between about 3.5 and about 7. |
| Inventor(s): | Benjamin; Eric (Dublin, OH), Anik; Shabbir (Mountain View, CA), Lin; Ya-Yun T. (Cupertino, CA) |
| Assignee: | Syntex (U.S.A.) Inc. (Palo Alto, CA) |
| Application Number: | 07/247,008 |
| Patent Claims: | 1. A stable, effectively preservable, substantially non-stinging aqueous anti-inflammatory steroid formulation suitable for intranasal administration, which formulation comprises: |
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ISSN: 2162-2639
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