Claims for Patent: 5,254,539
✉ Email this page to a colleague
Summary for Patent: 5,254,539
Title: | Method of treating HIV with 2',3'-dideoxyinosine |
Abstract: | A method for tearing retroviral infections including acquired immune deficiency syndrome (AIDS) with 2',3'-dideoxyinosine or 2',3'-dideoxyadenosine is disclosed. This antiviral effect is irreversible with 2',3'-dideoxyinosine and 2',3'-dideoxyadenosine but reversible with 2',3'-dideoxyguanosine. |
Inventor(s): | Mitsuya; Hiroaki (Rockville, MD), Broder; Samuel (Bethesda, MD) |
Assignee: | U.S. Government, Dept. of Health and Human Services, c/o National (Bethesda, MD) |
Application Number: | 07/663,288 |
Patent Claims: |
1. A method for treating an individual infected with human immunodeficiency virus, comprising administering a therapeutically effective amount of 2',3'-dideoxyinosine or a
pharmaceutically acceptable salt thereof, to said individual.
2. The method according to claim 1 wherein the therapeutically effective amount of 2',3'-dideoxyinosine is administered orally. 3. The method according to claim 1 wherein the therapeutically effective amount of 2',3'-dideoxyinosine is administered intravenously. 4. The method according to claim 1 wherein the therapeutically effective amount of 2',3'-dideoxyinosine is administered intramuscularly. 5. The method according to claim 1 wherein the therapeutically effective amount of 2',3'-dideoxyinosine is administered subcutaneously. 6. The method according to claim 1 wherein the 2',3'-dideoxyinosine is administered to the individual to achieve peak plasma concentrations ranging from about 0.5 uM to about 50 uM. 7. The method according to claim 1 in which the 2',3'-dideoxyinosine is administered to the individual to achieve peak plasma concentrations ranging from about 1 uM to about 30 uM. |
Make Better Decisions: Try a trial or see plans & pricing
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.