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Last Updated: December 22, 2024

Claims for Patent: 7,867,996

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Summary for Patent: 7,867,996

Title:	.gamma.-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
Abstract:	A .gamma.-Crystalline form of ivabradine hydrochloride of formula (I): ##STR00001## characterised by its powder X-ray diffraction data. Medicinal products containing the same which are useful as bradycardics.
Inventor(s):	Horvath; Stephane (La Chapelle-Saint-Mesmin, FR), Auguste; Marie-Noelle (Orleans, FR), Damien; Gerard (Meung-sur-Loire, FR)
Assignee:	Les Laboratories Servier (Suresnes Cedex, FR)
Application Number:	12/583,885
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,867,996
Patent Claims:	1. A .gamma.-Crystalline form of ivabradine hydrochloride of formula (I): ##STR00003## having a powder X-ray diffraction diagram exhibiting peaks at 4.2 and 13.4 deg 2 theta. 2. A .gamma.-Crystalline form of ivabradine hydrochloride of formula (I): ##STR00004## having a powder X-ray diffraction diagram exhibiting peaks at 4.2, 13.4, 21.1, 24.2, 24.5 and 26.4 deg 2 theta. 3. A solid pharmaceutical composition comprising as active ingredient the .gamma.-crystalline form of ivabradine hydrochloride of claim 1, in combination with one or more pharmaceutically acceptable, inert, non-toxic carriers. 4. A method for treating a condition selected from angina pectoris, myocardial infarct, and heart failure, such method comprising administering to a human, a therapeutically effective amount of the .gamma.-crystalline form of ivabradine hydrochloride of claim 1. 5. A solid pharmaceutical composition comprising as active ingredient the .gamma.-crystalline form of ivabradine hydrochloride of claim 2, in combination with one or more pharmaceutically acceptable, inert, non-toxic carriers. 6. A method for treating a condition selected from angina pectoris, myocardial infarct, and heart failure, such method comprising administering to a human, a therapeutically effective amount of the .gamma.-crystalline form of ivabradine hydrochloride of claim 2.

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