Details for Patent: 10,154,963
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Which drugs does patent 10,154,963 protect, and when does it expire?
Patent 10,154,963 protects SOAANZ and is included in one NDA.
This patent has two patent family members in two countries.
Summary for Patent: 10,154,963
Title: | Controlled-release formulations comprising Torsemide |
Abstract: | Disclosed herein are controlled-release (GR, e.g., extended-release (ER) or prolonged-release (PR)) oral dosage formulation comprising an effective amount of Torsemide or a pharmaceutically acceptable salt thereof and at least one sustained release excipient comprising a polymer, wherein the at least one matrix component is selected from the group consisting of: hydroxy propyl cellulose (HPC), hydroxpropyl methyl cellulose (HPMC), glyceryl behenate, and a polyethylene glycol glyceride. Torsemide may be present in the formulation in a range of about 1 wt % to about 20 wt %, or about 5 wt % to about 10 wt % and the matrix component is present in the formulation in a range of about 5 wt % to about 50 wt %, or about 15 wt % to about 35 wt %. The formulation may further comprise at least one binder, lactose, talc and magnesium stearate. Methods of making and using the controlled-release oral dosage Torsemide formulation are also disclosed. A novel mechanism for Torsemide action in diuresis is further disclosed. |
Inventor(s): | Shah; Salim (Vienna, VA) |
Assignee: | SARFEZ PHARMACEUTICALS, INC. (Vienna, VA) |
Application Number: | 15/027,355 |
Patent Claim Types: see list of patent claims | Use; Formulation; Compound; Delivery; Dosage form; |
Drugs Protected by US Patent 10,154,963
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sarfe Pharms | SOAANZ | torsemide | TABLET;ORAL | 213218-001 | Jun 14, 2021 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | ||||
Sarfe Pharms | SOAANZ | torsemide | TABLET;ORAL | 213218-002 | Jun 14, 2021 | DISCN | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | ⤷ Sign Up | ||||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 10,154,963
PCT Information | |||
PCT Filed | December 26, 2013 | PCT Application Number: | PCT/US2013/077732 |
PCT Publication Date: | April 09, 2015 | PCT Publication Number: | WO2015/050570 |
International Family Members for US Patent 10,154,963
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
European Patent Office | 3065718 | ⤷ Sign Up | |||
World Intellectual Property Organization (WIPO) | 2015050570 | ⤷ Sign Up | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |