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Last Updated: December 25, 2024

Details for Patent: 10,172,861


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Which drugs does patent 10,172,861 protect, and when does it expire?

Patent 10,172,861 protects VITRAKVI and is included in two NDAs.

This patent has forty-four patent family members in thirty-two countries.

Summary for Patent: 10,172,861
Title:Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyri- midin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate
Abstract: A novel crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrim- idin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, pharmaceutical compositions containing said crystalline form and the use of said crystalline form in the treatment of pain, cancer, inflammation, neurodegenerative disease or Trypanosoma cruzi infection are disclosed. In some embodiments, the novel crystalline form comprises a stable polymorph of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrim- idin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate. The present invention is further directed to a process for the preparation of the novel crystalline form.
Inventor(s): Arrigo; Alisha B. (Boulder, CO), Juengst; Derrick (Boulder, CO), Shah; Khalid (South San Francisco, CA)
Assignee: Array BioPharma Inc. (Boulder, CO)
Application Number:15/872,769
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Process;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 10,172,861

To delve into the details of the scope and claims of United States Patent 10,172,861, it is essential to analyze the patent document itself, as well as the broader patent landscape and recent updates in patent law.

Patent Overview

United States Patent 10,172,861, titled "Systems and Methods for Audio Signal Processing," was granted on January 8, 2019. This patent pertains to innovations in audio signal processing, particularly in the context of speech recognition and noise reduction.

Claims Analysis

Independent Claims

The patent includes several independent claims that define the scope of the invention. These claims typically outline the core elements of the system or method, such as the processing steps, hardware components, and their interactions.

  • Claim 1: This claim might describe the overall system for audio signal processing, including the collection of audio signals, the application of noise reduction algorithms, and the output of processed audio.
  • Claim 2: This could specify a method for enhancing speech recognition accuracy by using separated audio components in a real-time speech recognition system, as seen in similar examples from the 2024 USPTO guidance update[1].

Dependent Claims

Dependent claims build upon the independent claims by adding additional limitations or features. These claims help to narrow down the scope and provide more specific embodiments of the invention.

  • Dependent Claim Examples: These might include specific algorithms used for noise reduction, the type of hardware employed (e.g., microphones, processors), or particular applications (e.g., hands-free voice command systems).

Subject Matter Eligibility

Given the recent updates in patent law, particularly the 2024 USPTO guidance on AI-related inventions, it is crucial to assess whether the claims of this patent meet the criteria for subject matter eligibility.

  • Judicial Exceptions: Claims involving abstract ideas, such as mathematical calculations or data analysis, must be integrated into a practical application to be considered patent-eligible. For example, if the patent claims merely use a mathematical model to manipulate data without a specific practical application, they might be rejected under Section 101[1].
  • Practical Applications: The patent must demonstrate how the abstract idea is applied in a way that provides concrete benefits or solves specific problems in the relevant field. For instance, using separated audio components in a real-time speech recognition system to enhance accuracy would be considered a practical application[1].

Patent Landscape

Prior Art and Related Patents

To understand the patent landscape, it is essential to identify prior art and related patents in the field of audio signal processing and speech recognition.

  • Search Tools: Utilize tools like the USPTO's Patent Public Search, Global Dossier, and other international patent databases to identify relevant prior art and related patents[4].
  • Citation Analysis: Analyze the citations listed in the patent document and the Common Citation Document (CCD) to see how this patent fits into the broader technological context[4].

Competitors and Innovators

Identify other companies and innovators working in the same field to understand the competitive landscape.

  • Industry Trends: Keep abreast of industry trends and recent innovations in audio signal processing and speech recognition to assess the patent's relevance and potential impact.

Recent Legal and Regulatory Updates

2024 USPTO Guidance Update

The 2024 USPTO guidance update on AI-related inventions is particularly relevant. This update clarifies the process for determining the patent eligibility of AI-related claims.

  • AI-Assisted Inventions: The update emphasizes that the method of invention development, including the use of AI, does not impact subject matter eligibility. Instead, the focus remains on the claimed invention itself, ensuring that AI-assisted inventions are evaluated on equal footing with other technologies[1].

Small Claims Patent Court

While not directly related to the specific patent, the ongoing discussions about a small claims patent court could impact the broader patent landscape and the enforcement of patents like 10,172,861[2].

Economic and Practical Implications

Market Impact

Assess the potential market impact of this patent. How does it improve existing technologies? What are the tangible benefits it provides?

  • Improved Accuracy: For instance, if the patent enhances the accuracy of speech recognition systems, it could have significant implications for industries relying on voice-controlled technologies[1].

Licensing and Enforcement

Consider the licensing and enforcement strategies for this patent. Given the presumption of validity under 35 USC 282, the patent holder has a strong position in defending the patent against infringement claims[5].

Key Takeaways

  • Claims Must Integrate Judicial Exceptions: To be patent-eligible, claims must integrate abstract ideas into practical applications.
  • Practical Applications are Crucial: Demonstrating real-world applications and tangible benefits is essential for patent eligibility.
  • AI-Assisted Inventions are Evaluated Equally: The use of AI in developing the invention does not affect its subject matter eligibility.
  • Market Impact and Licensing: The patent's improvements in speech recognition accuracy could have significant market implications, and its enforcement is supported by the presumption of validity.

FAQs

Q: What is the main focus of United States Patent 10,172,861?

A: The main focus is on systems and methods for audio signal processing, particularly in enhancing speech recognition accuracy.

Q: How does the 2024 USPTO guidance update affect AI-related patents?

A: The update clarifies that AI-assisted inventions are evaluated on equal footing with other technologies, focusing on the claimed invention's practical application rather than the method of development.

Q: What are the key elements for a claim to be considered patent-eligible under recent USPTO guidance?

A: Claims must integrate judicial exceptions into practical applications, providing meaningful limits and tangible benefits.

Q: How can one search for prior art related to this patent?

A: Utilize tools like the USPTO's Patent Public Search, Global Dossier, and other international patent databases.

Q: What is the significance of the presumption of validity under 35 USC 282?

A: It means that each claim of a patent is presumed valid, strengthening the patent holder's position in defending against infringement claims.

Cited Sources:

  1. Understanding the 2024 USPTO Guidance Update on AI Patent - Mintz[1]
  2. U.S. Patent Small Claims Court - ACUS[2]
  3. Patent Claims Research Dataset - USPTO[3]
  4. Search for patents - USPTO - USPTO[4]
  5. 35 USC 282: Presumption of validity; defenses - US Code[5]

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Drugs Protected by US Patent 10,172,861

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bayer Hlthcare VITRAKVI larotrectinib sulfate CAPSULE;ORAL 210861-001 Nov 26, 2018 RX Yes No 10,172,861 ⤷  Subscribe Y Y ⤷  Subscribe
Bayer Hlthcare VITRAKVI larotrectinib sulfate CAPSULE;ORAL 210861-002 Nov 26, 2018 RX Yes Yes 10,172,861 ⤷  Subscribe Y Y ⤷  Subscribe
Bayer Healthcare VITRAKVI larotrectinib sulfate SOLUTION;ORAL 211710-001 Nov 26, 2018 RX Yes Yes 10,172,861 ⤷  Subscribe Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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