Details for Patent: 11,236,328
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Which drugs does patent 11,236,328 protect, and when does it expire?
Patent 11,236,328 protects DEFITELIO and is included in one NDA.
This patent has twenty-five patent family members in sixteen countries.
Summary for Patent: 11,236,328
| Title: | Euglobulin-based method for determining the biological activity of defibrotide |
| Abstract: | It is disclosed a method for determining the biological activity of defibrotide, which comprises the steps of: a) bringing into contact defibrotide, mammalian euglobulin and a substrate specific for the plasmin which, by reaction with the plasmin, provides a measurable product; and b) measuring the amount of product formed at successive times, to thereby determine the biological activity of the defibrotide. Liquid defibrotide formulations are also disclosed, preferably water solutions, having a defined biological activity and, in particular, having an activity of 25 to 35 IU/mg of defibrotide, preferably from 27 to 32 IU/mg and, more preferably, from 28 to 32 IU/mg. |
| Inventor(s): | Ignoni; Terenzio (Solbiate, IT), Kumar; Vijay (Casnate, IT), Islam; Khalid (Massagno, IT) |
| Assignee: | GENTIUM S.R.L. (Villa Guardia, IT) |
| Application Number: | 17/459,169 |
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Patent Claim Types: see list of patent claims | Use; Formulation; |
Drugs Protected by US Patent 11,236,328
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jazz Pharms Inc | DEFITELIO | defibrotide sodium | SOLUTION;INTRAVENOUS | 208114-001 | Mar 30, 2016 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | TREATMENT OF ADULT AND PEDIATRIC PATIENTS WITH HEPATIC VENO-OCCLUSIVE DISEASE (VOD), ALSO KNOWN AS SINUSOIDAL OBSTRUCTION SYNDROME (SOS), WITH RENAL OR PULMONARY DYSFUNCTION FOLLOWING HEMATOPOIETIC STEM-CELL TRANSPLANTATION (HSCT) | ⤷ Sign Up | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 11,236,328
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2012383169 | ⤷ Sign Up | |||
| Brazil | 112014031934 | ⤷ Sign Up | |||
| Canada | 2874960 | ⤷ Sign Up | |||
| China | 104619857 | ⤷ Sign Up | |||
| China | 110079580 | ⤷ Sign Up | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
