Details for Patent: 11,365,182

Which drugs does patent 11,365,182 protect, and when does it expire?

Patent 11,365,182 protects BYLVAY and is included in one NDA.

This patent has forty-one patent family members in twenty countries.

Summary for Patent: 11,365,182

Title:	Crystal modifications of odevixibat
Abstract:	The present invention relates to crystal modifications of 1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N--{(R)-.alpha.-[N--((S)-1- -carboxypropyl)carbamoyl]-4-hydroxybenzyl}carbamoylmethoxy)-2,3,4,5-tetrah- ydro-1,2,5-benzothiadiazepine (odevixibat), more specifically crystal modifications 1 and 2 of odevixibat. The invention also relates to a process for the preparation of crystal modification 1 of odevixibat, to a pharmaceutical composition comprising crystal modification 1, and to the use of this crystal modification in the treatment of various conditions as described herein.
Inventor(s):	Lundqvist; Robert (Halso, SE), Ymen; Ingvar (Saltsjo-boo, SE), Bohlin; Martin (Johanneshov, SE), Byrod; Eva (Molndal, SE), Gillberg; Per-Goran (Molndal, SE), Tivert; Anna-Maria (Gothenburg, SE), Bryland; Rikard (Limhamn, SE), Dahlquist; Ann-Charlotte (Lund, SE), Elversson; Jessica (Dalby, SE), Gustafsson; Nils Ove (Loddekopinge, SE)
Assignee:	Albireo AB (Gothenburg, SE)
Application Number:	17/065,245
Patent Claim Types: see list of patent claims	Use;

Drugs Protected by US Patent 11,365,182

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Ipsen	BYLVAY	odevixibat	CAPSULE, PELLETS;ORAL	215498-001	Jul 20, 2021		RX	Yes	No						METHOD OF REDUCING SERUM BILE ACIDS IN PATIENTS 12 MONTHS OR OLDER SUFFERING FROM ALAGILLE SYNDROME (ALGS)
Ipsen	BYLVAY	odevixibat	CAPSULE, PELLETS;ORAL	215498-001	Jul 20, 2021		RX	Yes	No						METHOD OF TREATING CHOLESTATIC PRURITUS IN PATIENTS 12 MONTHS OR OLDER SUFFERING FROM ALAGILLE SYNDROME (ALGS)
Ipsen	BYLVAY	odevixibat	CAPSULE, PELLETS;ORAL	215498-001	Jul 20, 2021		RX	Yes	No						METHOD OF TREATING PRURITUS IN PATIENTS 3 MONTHS OR OLDER SUFFERING FROM PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS (PFIC)
Ipsen	BYLVAY	odevixibat	CAPSULE, PELLETS;ORAL	215498-001	Jul 20, 2021		RX	Yes	No						METHOD OF REDUCING SERUM BILE ACIDS IN PATIENTS 3 MONTHS OR OLDER SUFFERING FROM PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS (PFIC)

Foreign Priority and PCT Information for Patent: 11,365,182

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Sweden	1850761-6	Jun 20, 2018
Sweden	1850762-4	Jun 20, 2018

International Family Members for US Patent 11,365,182

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2019290337
Australia	2019290338
Brazil	112020024461
Brazil	112020024479