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Last Updated: December 22, 2024

Details for Patent: 11,524,951


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Summary for Patent: 11,524,951
Patent landscape, scope, and claims:
Title:2-(2,4,5-substituted-anilino)pyrimidine compounds
Abstract:The present invention relates to certain 2-(2,4,5-substituted-anilino)pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exon19 deletion activating mutant and the T790M resistance mutant). Such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers. The invention also relates to pharmaceutical compositions comprising said compounds and salts thereof, especially useful polymorphic forms of these compounds and salts, intermediates useful in the manufacture of said compounds and to methods of treatment of diseases mediated by various different forms of EGFR using said compounds and salts thereof.
Inventor(s):Butterworth Sam, Finlay Maurice Raymond Verschoyle, Ward Richard Andrew, Redfearn Heather Marie, Kadambar Vasantha Krishna, Chintakuntla Chandrasekhara Reddy, Murugan Andiappan, Chuaqui Claudio Edmundo
Assignee:AstraZeneca AB
Application Number:US17096167
Patent Claim Types:
see list of patent claims
 

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Drugs Protected by US Patent 11,524,951

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astrazeneca TAGRISSO osimertinib mesylate TABLET;ORAL 208065-001 Nov 13, 2015 RX Yes No ⤷  Subscribe ⤷  Subscribe Y Y ⤷  Subscribe
Astrazeneca TAGRISSO osimertinib mesylate TABLET;ORAL 208065-002 Nov 13, 2015 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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