United States Patent 11,691,948: A Detailed Analysis of Scope, Claims, and Patent Landscape
Introduction
United States Patent 11,691,948, titled "Crystalline freebase forms of a biphenyl compound," is a significant patent in the pharmaceutical sector, particularly in the treatment of pulmonary disorders. This article provides a comprehensive analysis of the patent's scope, claims, and the broader patent landscape it operates within.
Patent Overview
Invention Description
The patent pertains to crystalline freebase forms of a biphenyl compound, specifically biphenyl-2-ylcarbamic acid 1-(2-[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylaminoethyl)piperidin-4-yl ester. This compound exhibits muscarinic receptor antagonist activity, making it useful for treating pulmonary disorders such as asthma and chronic obstructive pulmonary disease (COPD)[4].
Key Aspects of the Invention
- Pharmaceutical Compositions: The patent includes pharmaceutical compositions comprising the crystalline freebase of the biphenyl compound, along with a pharmaceutically acceptable carrier.
- Methods of Treatment: It covers methods for treating pulmonary disorders by administering a therapeutically effective amount of the crystalline freebase.
- Processes for Preparation: The patent details processes for preparing and purifying the crystalline freebase forms of the compound.
- Physical Properties: The crystalline freebase forms are noted for their stability, not being deliquescent, and having acceptable levels of hygroscopicity and melting points[4].
Scope of the Patent
Claims
The patent includes several claims that define the scope of the invention:
- Compound Claims: Claims related to the crystalline freebase forms of the biphenyl compound, including specific polymorphs (Form III and Form IV).
- Composition Claims: Claims covering pharmaceutical compositions that include the crystalline freebase and a pharmaceutically acceptable carrier.
- Method Claims: Claims pertaining to methods of treating pulmonary disorders and antagonizing muscarinic receptors using the crystalline freebase.
- Process Claims: Claims related to the preparation and purification of the crystalline freebase forms[4].
Prior Art and Novelty
The patent distinguishes itself from prior art by the specific crystalline freebase forms of the biphenyl compound and their unique properties, such as stability and melting points. The novelty lies in the identification and characterization of these forms, which are crucial for pharmaceutical applications[4].
Patent Landscape
Global Patent System
The patent is part of a broader global patent system. To understand its position, one must consider international patent databases and services:
- USPTO Resources: The USPTO provides tools like the Patent Public Search and Global Dossier, which help in searching and analyzing patent families across different jurisdictions[1].
- International Databases: Databases such as those from the European Patent Office (EPO), Japan Patent Office (JPO), and World Intellectual Property Organization (WIPO) are essential for a comprehensive search of prior art and related patents[1].
Related Patents and Applications
The patent is part of a larger family of patents related to pharmaceutical compounds and their applications. Searching through databases like PATENTSCOPE and esp@cenet can reveal similar patents and applications that may impact the scope and validity of this patent[1].
Economic and Legal Implications
Economic Impact
The economic impact of this patent is significant, given the potential market for treatments of pulmonary disorders like asthma and COPD. The stability and efficacy of the crystalline freebase forms make them valuable assets for pharmaceutical companies.
- Market Dominance: Holding this patent can provide a competitive edge in the market, allowing the patent holder to dominate the segment for treatments using this specific compound[4].
Legal Considerations
- Litigation: The patent could be involved in litigation, as seen in cases where patent rights are contested. For example, any infringement or validity challenges would need to be addressed through legal proceedings[5].
- Expiration Dates: Understanding the expiration dates of the patent is crucial for planning future strategies. The patent's legal status and expiration dates are critical for both the patent holder and potential competitors[2].
Search and Analysis Tools
USPTO Resources
- Patent Public Search: This tool provides enhanced access to prior art and is essential for conducting a preliminary patent search[1].
- Global Dossier: This service allows users to view the file histories of related applications from participating IP Offices, which is useful for analyzing the patent family and related citations[1].
International Resources
- PATENTSCOPE: This WIPO service offers full-text search of published international patent applications and machine translations, aiding in global patent searches[1].
- esp@cenet: The EPO's database provides access to Europe's patent databases and machine translations, further facilitating international patent searches[1].
Key Takeaways
- Specific Crystalline Forms: The patent focuses on specific crystalline freebase forms of a biphenyl compound, which are stable and have defined physical properties.
- Pharmaceutical Applications: The invention is primarily aimed at treating pulmonary disorders like asthma and COPD.
- Global Patent Landscape: The patent is part of a broader global patent system, and its analysis requires consideration of international databases and services.
- Economic and Legal Implications: The patent has significant economic and legal implications, including market dominance and potential litigation.
FAQs
What is the main subject of United States Patent 11,691,948?
The main subject of this patent is the crystalline freebase forms of a biphenyl compound, specifically biphenyl-2-ylcarbamic acid 1-(2-[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylaminoethyl)piperidin-4-yl ester.
What are the key claims of this patent?
The key claims include those related to the crystalline freebase forms of the compound, pharmaceutical compositions, methods of treatment for pulmonary disorders, and processes for preparation and purification.
How does this patent distinguish itself from prior art?
The patent distinguishes itself through the identification and characterization of specific crystalline freebase forms of the biphenyl compound, which exhibit unique properties such as stability and defined melting points.
What tools can be used to analyze the patent landscape for this invention?
Tools such as the USPTO's Patent Public Search, Global Dossier, PATENTSCOPE, and esp@cenet can be used to analyze the patent landscape and search for related patents and applications.
What are the economic implications of holding this patent?
Holding this patent can provide a competitive edge in the market for treatments of pulmonary disorders, allowing the patent holder to dominate this segment due to the stability and efficacy of the crystalline freebase forms.
Sources
- USPTO - Search for patents: https://www.uspto.gov/patents/search
- PharmaCompass - US Patent 11691948: https://www.pharmacompass.com/us-patent-11691948
- USPTO - Patent Claims Research Dataset: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
- Google Patents - US11691948B2: https://patents.google.com/patent/US11691948B2/en
- Insight.RPXcorp - Litigation Documents: https://insight.rpxcorp.com/litigation_documents/15344236
