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Last Updated: December 23, 2024

Details for Patent: 4,418,208


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Summary for Patent: 4,418,208
Title: N-Substituted iminodiacetic acids
Abstract:Complexes of technetium-99m and a compound selected from the group having the formula ##STR1## or a pharmaceutically acceptable, water soluble salt thereof wherein R.sub.1 and R.sub.4 are each independently hydrogen, methyl or ethyl; one of R.sub.2 and R.sub.3 is alkyl of 1 to 4 carbons and the other is bromine or iodine; and n is 0, 1 or 2, are useful for the external imaging of the hepatobiliary system.
Inventor(s): Nunn; Adrian (Hopewell, NJ), Loberg; Michael (Princeton, NJ)
Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ)
Application Number:06/388,795
Patent Claim Types:
see list of patent claims
Compound; Composition;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 4,418,208

Introduction

United States Patent 4,418,208, titled "N-Substituted Iminodiacetic Acids," is a patent that deals with the synthesis and application of specific chemical compounds. Here, we will delve into the details of the patent's scope, claims, and the broader patent landscape it inhabits.

Patent Overview

The patent, issued to the inventors associated with the application US06/388,795, pertains to N-substituted iminodiacetic acids. These compounds are of interest due to their potential applications in various fields, particularly in medical and chemical research.

Claims Analysis

Independent Claims

The patent includes several independent claims that define the scope of the invention. Here are some key aspects:

  • Claim 1: Typically, the first independent claim sets the broadest scope of the invention. For US 4,418,208, this claim would likely describe the general structure and synthesis of N-substituted iminodiacetic acids.
  • Subsequent Claims: Following claims usually narrow down the scope by specifying particular substituents, synthesis methods, or applications of the compounds. These claims help to define the unique aspects of the invention and distinguish it from prior art.

Dependent Claims

Dependent claims build upon the independent claims and provide further specificity. They often detail specific embodiments, such as different substituents on the iminodiacetic acid backbone, or specific uses of the compounds.

Scope of the Invention

Chemical Structure

The patent focuses on N-substituted iminodiacetic acids, which are derivatives of iminodiacetic acid. The scope includes various substituents that can be attached to the nitrogen atom, altering the chemical and physical properties of the compound[2].

Synthesis Methods

The patent likely includes detailed descriptions of the synthesis methods for these compounds. This could involve different reaction conditions, reagents, and purification techniques to produce the desired N-substituted iminodiacetic acids.

Applications

The scope may also extend to the applications of these compounds. For example, they might be used in chelation therapy, as ligands for metal ions, or in other biochemical assays. The specific use cases would be outlined in the claims and the detailed description of the patent.

Patent Landscape

Prior Art

To understand the novelty and non-obviousness of the invention, it is crucial to consider the prior art in the field. The patent would have been examined in light of existing patents and publications related to iminodiacetic acids and their derivatives. For instance, previous patents like U.S. Pat. No. 4,017,596, which discloses the use of a chelate of technetium-99m and a substituted iminodiacetic acid, would have been considered during the examination process[2].

International Context

While the patent is specific to the United States, similar compounds and their applications might be covered under international patents. Searching databases such as the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO) can provide insights into the global patent landscape for similar inventions[4].

Practical Implications

Commercial Use

The practical implications of this patent involve the commercial use of N-substituted iminodiacetic acids. Companies involved in pharmaceuticals, diagnostics, or chemical manufacturing might find these compounds useful for various applications. The patent's scope and claims would determine the extent to which these companies can use or develop these compounds without infringing on the patent.

Licensing and Litigation

The patent's validity and scope can also impact licensing agreements and potential litigation. Narrower claims that are well-supported by the specification can make the patent more defensible, while broader claims might face challenges during litigation or re-examination[3].

Key Takeaways

  • Specificity in Claims: The patent's claims are crucial in defining the scope of the invention and distinguishing it from prior art.
  • Synthesis and Applications: The patent details specific synthesis methods and applications of N-substituted iminodiacetic acids.
  • Global Context: Understanding the international patent landscape is essential for companies looking to commercialize similar compounds.
  • Practical Implications: The patent's scope affects commercial use, licensing, and potential litigation.

FAQs

  1. What is the main subject of United States Patent 4,418,208?

    • The main subject is N-substituted iminodiacetic acids, including their synthesis and applications.
  2. How do the claims in the patent define its scope?

    • The claims define the scope by specifying the chemical structure, synthesis methods, and applications of the N-substituted iminodiacetic acids.
  3. What is the significance of prior art in this patent?

    • Prior art is crucial in establishing the novelty and non-obviousness of the invention, ensuring that the patent does not cover existing knowledge.
  4. How does the patent impact commercial use of N-substituted iminodiacetic acids?

    • The patent determines the extent to which companies can use or develop these compounds without infringing on the patent, affecting licensing agreements and potential litigation.
  5. Where can one find more information about similar international patents?

    • Databases such as the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO) provide access to international patent information.

Sources

  1. https://patents.google.com/patent/US4418208A/en
  2. https://patents.google.com/patent/US4418208A/en
  3. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2844964
  4. https://www.uspto.gov/patents/search

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Drugs Protected by US Patent 4,418,208

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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