Details for Patent: 4,681,893

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Summary for Patent: 4,681,893

Title:	Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
Abstract:	Certain trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-ones and the corresponding ring-opened acids derived therefrom which are potent inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG CoA reductase and are thus useful hypolipidemic or hypocholesterolemic agents. Pharmaceutical compositions containing such compounds, and a method of inhibiting the biosynthesis of cholesterol employing such pharmaceutical compositions are also disclosed.
Inventor(s):	Roth; Bruce D. (Ann Arbor, MI)
Assignee:	Warner-Lambert Company (Morris Plains, NJ)
Application Number:	06/868,867
Patent Claim Types: see list of patent claims	Compound; Composition; Use;

Drugs Protected by US Patent 4,681,893

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>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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European Patent Office	0247633	⤷ Sign Up	SPC/GB97/011	United Kingdom	⤷ Sign Up
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European Patent Office	0247633	⤷ Sign Up	9790036	Sweden	⤷ Sign Up
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