Details for Patent: 4,717,720

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Summary for Patent: 4,717,720

Title:	Benzonaphthalene derivatives and compositions
Abstract:	A benzonaphthalene compound has the formula ##STR1## wherein R.sub.1 represents (i) ##STR2## or (ii) --CH.sub.2 OH; R.sub.6 represents ##STR3## or OR.sub.7 wherein R.sub.7 represents hydrogen, alkyl having 1-20 carbon atoms, monohydroxyalkyl or polyhydroxyalkyl, r' or r" represent hydrogen, lower alkyl, mono or polyhydroxyalkyl, aryl or a residue of an amino acid or a sugar, or together form a heterocycle; R.sub.2 represents hydrogen, alkyl having 1-15 carbon atoms, alkoxy having 1-4 carbon atoms or a cycloaliphatic radical; R.sub.3 represents hydrogen, hydroxy, alkyl having 1-4 carbon atoms, alkoxy having 1-10 carbon atoms, a cycloaliphatic radical, a thiocycloaliphatic radical or --O--Si(CH.sub.3).sub.2 --R.sub.8 wherein R.sub.8 represents lower alkyl; and R.sub.4 and R.sub.5 represent hydrogen, lower alkyl, hydroxy or lower acyloxy. This compound is useful in the topical and systemic treatment of dermatologic diseases and in the treatment of the degeneration of conjuctive tissues. The compound also possesses anti-tumor activity.
Inventor(s):	Shroot; Braham (Antibes, FR), Eustache; Jacques (Grasse, FR), Bernardon; Jean-Michel (Nice, FR)
Assignee:	Centre International de Recherches Dermatologiques (C.I.R.D.) (Valbonne, FR)
Application Number:	06/850,145
Patent Claim Types: see list of patent claims	Compound; Composition;

Drugs Protected by US Patent 4,717,720

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Foreign Priority and PCT Information for Patent: 4,717,720

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Luxembourg	85849	Apr 11, 1985

International Family Members for US Patent 4,717,720

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