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Last Updated: December 22, 2024

Details for Patent: 4,966,891


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Summary for Patent: 4,966,891
Patent landscape, scope, and claims:
Title: Fluorocytidine derivatives
Abstract:The novel 5'-deoxy-5-fluorocytidine derivatives of formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen or an easily hydrolyzable radical under physiological conditions, with the proviso that, at least one or R.sup.1, R.sup.2 and R.sup.3 is an easily hydrolyzable radical under physiological conditions, as well as hydrates of solvates of these compounds have antitumor properties. They can be prepared from compounds of formula I, wherein R.sup.1 is hydrogen or an amino-protecting radical and R.sup.2 and R.sup.3 are hydrogen or a hydroxy-protecting radical or taken together are a cyclic hydroxy-protecting radical.
Inventor(s): Fujiu; Morio (Chigasaki, JP), Ishitsuka; Hideo (Yokohama, JP), Miwa; Masanori (Kamakura, JP), Umeda; Isao (Yokohama, JP), Yokose; Kazuteru (Urayasu, JP)
Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Application Number:07/268,437
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

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Drugs Protected by US Patent 4,966,891

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 4,966,891

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
87116926.4Nov 17, 1987

International Family Members for US Patent 4,966,891

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0316704 ⤷  Subscribe SPC/GB01/015 United Kingdom ⤷  Subscribe
European Patent Office 0316704 ⤷  Subscribe C300045 Netherlands ⤷  Subscribe
European Patent Office 0316704 ⤷  Subscribe 2001C/021 Belgium ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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