Details for Patent: 4,966,891
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Summary for Patent: 4,966,891
Title: | Fluorocytidine derivatives |
Abstract: | The novel 5'-deoxy-5-fluorocytidine derivatives of formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are hydrogen or an easily hydrolyzable radical under physiological conditions, with the proviso that, at least one or R.sup.1, R.sup.2 and R.sup.3 is an easily hydrolyzable radical under physiological conditions, as well as hydrates of solvates of these compounds have antitumor properties. They can be prepared from compounds of formula I, wherein R.sup.1 is hydrogen or an amino-protecting radical and R.sup.2 and R.sup.3 are hydrogen or a hydroxy-protecting radical or taken together are a cyclic hydroxy-protecting radical. |
Inventor(s): | Fujiu; Morio (Chigasaki, JP), Ishitsuka; Hideo (Yokohama, JP), Miwa; Masanori (Kamakura, JP), Umeda; Isao (Yokohama, JP), Yokose; Kazuteru (Urayasu, JP) |
Assignee: | Hoffmann-La Roche Inc. (Nutley, NJ) |
Application Number: | 07/268,437 |
Patent Claim Types: see list of patent claims | Compound; Use; Composition; | More… ↓ |
Drugs Protected by US Patent 4,966,891
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,966,891
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
87116926.4 | Nov 17, 1987 |
International Family Members for US Patent 4,966,891
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
European Patent Office | 0316704 | ⤷ Subscribe | SPC/GB01/015 | United Kingdom | ⤷ Subscribe |
European Patent Office | 0316704 | ⤷ Subscribe | C300045 | Netherlands | ⤷ Subscribe |
European Patent Office | 0316704 | ⤷ Subscribe | 2001C/021 | Belgium | ⤷ Subscribe |
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |