Details for Patent: 5,013,556
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Summary for Patent: 5,013,556
Title: | Liposomes with enhanced circulation time |
Abstract: | A liposome composition which contains between 1-20 mole percent of an amphipathic lipid derivatized with a polyalkylether, as exemplified by phosphatidylethanolamine derivatized with polyethyleneglycol. The derivatized lipid enchances the circulation time of the liposomes severalfold, and this enhancement is achieved with either fluid or membrane-rigidifying liposome components. Also disclosed are methods for delivering a drug for slow release from the bloodstream, and for targeting a selected tissue or cells with liposomes, via the bloodstream. |
Inventor(s): | Woodle; Martin C. (Menlo Park, CA), Martin; Francis J. (San Francisco, CA), Yau-Young; Annie (Los Altos, CA), Redemann; Carl T. (Walnut Creek, CA) |
Assignee: | Liposome Technology, Inc. (Menlo Park, CA) |
Application Number: | 07/425,224 |
Patent Claim Types: see list of patent claims | Composition; Dosage form; Delivery; Compound; Use; |
Drugs Protected by US Patent 5,013,556
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International Family Members for US Patent 5,013,556
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European Patent Office | 0496835 | ⤷ Sign Up | 960031 | Netherlands | ⤷ Sign Up |
European Patent Office | 0496835 | ⤷ Sign Up | SPC/GB96/053 | United Kingdom | ⤷ Sign Up |
European Patent Office | 0496835 | ⤷ Sign Up | C960031 | Netherlands | ⤷ Sign Up |
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